Zn Nanoparticles Modified Screen Printed Carbon Electrode as a Promising Sensor for Insulin Determination

Šišoláková, Ivana; Hovancová, Jana; Chovancová, Frederika; Oriňáková, Renáta; Maskaľová, Iveta; Oriňák, Andrej; Radonák, J

doi:10.1002/elan.202060417

Cited by 9 publications

(2 citation statements)

References 38 publications

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“…I) než předchozí uvedené nanokompozitní SPCE, tak ostatní analytické parametry (tab. I) jsou podobné 66 . Podle našich úvah do elektrokatalytického procesu v alkalickém prostředí vstupují nanočástice ne v podobě čistého kovu, ale v podobě jeho příslušného oxidu.…”

Section: Neenzymové Elektrochemické Senzory Pro Stanovení Insulinuunclassified

Electroanalysis of Insulin on Nanocomposite Electrodes

Trnková,

Třísková

2023

Chem. Listy

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The article notes the latest presented work on the electrochemical detection of insulin and presents a critical view of the research and development of its electrochemical non-enzymatic sensors. It monitors the effect of experimental conditions on the insulin oxidation signal and considers the catalytic effects of nanoparticles or nanocomposites deposited on the surfaces of the electrochemical sensor.

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Section: Neenzymové Elektrochemické Senzory Pro Stanovení Insulinuunclassified

Electroanalysis of Insulin on Nanocomposite Electrodes

Trnková,

Třísková

2023

Chem. Listy

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“…The current response increases with both the addition of multi-walled carbon nanotubes (MWCNTs) and the electrochemical deposition of NiO nanoparticles. The Randles-Ševčík equation was used for an exact calculation of the electroactive surface area [25]:…”

Section: Active Surface Area and Electrochemical Mechanism Studymentioning

confidence: 99%

NiO Nanoparticles for Electrochemical Insulin Detection

Shepa

Šišoláková

Vojtko

et al. 2021

Sensors

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Diabetes mellitus represents one of the most widespread diseases in civilization nowadays. Since the costs for treating and diagnosing of diabetes represent several billions of dollars per year, a cheap, fast, and simple sensor for diabetes diagnosis is needed. Electrochemical insulin sensors can be considered as a novel approach for diabetes diagnosis. In this study, carbon electrode with electrodeposited NiO nanoparticles was selected as a suitable electrode material for insulin determination. The morphology and surface composition were studied by scanning electron microscopy (SEM), energy dispersive X-ray (EDX) spectroscopy, and X-ray photoelectron spectroscopy (XPS). For a better understanding of insulin determination on NiO-modified electrodes, the mechanism of electrochemical reaction and the kinetic parameters were studied. They were calculated from both voltammetric and amperometric measurements. The modified carbon electrode displayed a wide linear range from 600 nM to 10 µM, a low limit of detection of 19.6 nM, and a high sensitivity of 7.06 µA/µM. The electrodes were stable for 30 cycles and were able to detect insulin even in bovine blood serum. Additionally, the temperature stability of this electrode and its storage conditions were studied with appropriate outcomes. The above results show the high promise of this electrode for detecting insulin in clinical samples.

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Electrochemical traditions in Eastern Europe

Péter

Tsirlina

2023

J Solid State Electrochem

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Zn Nanoparticles Modified Screen Printed Carbon Electrode as a Promising Sensor for Insulin Determination

Cited by 9 publications

References 38 publications

Electroanalysis of Insulin on Nanocomposite Electrodes

Electroanalysis of Insulin on Nanocomposite Electrodes

NiO Nanoparticles for Electrochemical Insulin Detection

Electrochemical traditions in Eastern Europe

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