Zn²⁺ Recognition for Pathogenesis of Pick's Disease via a Luminescent Test Kit

Abstract

The pathogenesis of Pick's disease is feasible by detection of the elevated level of Zn 2 + in the body fluids. This work aims towards developing a suitable chemosensor towards detection of Zn 2 + in human urine specimen and inside eukaryotic cell line. Fluorescence "turn on" in the presence of Zn 2 + makes the chemosensor suitable for its utility in Pick's disease diagnosis. Real urine sample analysis together within cell detection of Zn 2 + was successful which leads towards the design and fabrication of a "ready-to-use" test kit for Zn 2 + recognition from human urine specimen.