Zur Komorbidität von Posttraumatischer Belastungsstörung und Sucht in biopsychosozialer Perspektive

Kapfhammer, Hans-Peter

doi:10.1007/s40211-020-00384-4

Cited by 9 publications

(2 citation statements)

References 204 publications

(238 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…First, a common biological dysfunction or vulnerability might increase the likelihood to develop either disorder in the course of their life [ 9 ] (given the appropriate environmental variables, such as a traumatic events), as indicated by data showing that both disorders have a similar age of onset, namely around adolescence [ 10 ]. Accordingly, some studies have found genetic markers that are related to PTSD as well as SUD, such as polymorphism of the GABA receptor [ 11 – 13 ]. Second, circumstances promoting development of SUD in adolescents often include adverse life events or traumatic experiences (TEs) [ 14 ], and this increased exposure to TEs might also facilitate the development of PTSD [ 15 , 16 ].…”

Section: Introductionmentioning

confidence: 99%

Coping motives mediate the relationship between PTSD and MDMA use in adolescents with substance use disorders

Basedow

Wiedmann

Roessner

et al. 2022

Addict Sci Clin Pract

View full text Add to dashboard Cite

Background Post-traumatic stress disorder (PTSD) and substance use disorders (SUDs) often co-occur in adolescent patients. Previous research has shown that these patients differ from SUD patients without PTSD in terms of their substance use patterns. In this study, we aimed to test whether substance use in this population is related to an attempt to self-medicate PTSD-related symptoms. Methods German adolescent patients (aged 13–18 years) at an outpatient clinic for SUD treatment, n = 111 (43% female), completed a self-designed questionnaire on use motives, a measure of PTSD-related experiences, and underwent a standardized psychiatric interview including structured substance use questions. Participants were subsequently classified as ‘no traumatic experiences (‘noTEs’ but SUD), ‘traumatic experiences but no current PTSD diagnosis’ (‘TEs’ with SUD), and ‘PTSD’ with SUD. After establishing a self-designed motive measurement through exploratory and confirmatory factor analyses, we calculated non-parametric group differences and a mediation analysis in a linear regression framework. Results The past-year frequency of MDMA use was highest in the PTSD group and lowest in the noTE group (H (2) = 7.2, p = .027, η2 = .058), but no differences were found for frequencies of tobacco, alcohol, cannabis, or stimulant use (all H ≤ 4.9, p ≥ .085, η2 ≤ .033). While controlling for sex, the three groups showed a similar pattern (highest in the PTSD group and lowest in the noTE group) for coping scores (F (103) = 5.77, p = .004, η2 = .101). Finally, mediation analyses revealed an indirect effect of coping score (b = 0.61, 95% CI [0.29, 1.58], p = .145) on the association between group membership and MDMA use frequency. Conclusions In adolescent SUD patients, we found an association of current PTSD and lifetime traumatic experiences with higher MDMA use that could be partially explained by substance use being motivated by an attempt to cope with mental health symptoms. This indicates a coping process involved specifically in MDMA use compared to the use of other psychoactive substances, possibly due to unique psychoactive effects of MDMA.

show abstract

Section: Introductionmentioning

confidence: 99%

Coping motives mediate the relationship between PTSD and MDMA use in adolescents with substance use disorders

Basedow

Wiedmann

Roessner

et al. 2022

Addict Sci Clin Pract

View full text Add to dashboard Cite

show abstract

“…There are several adverse effects of substance abuse on the consumers themselves and the social context in which they live. These include physical and mental comorbidities as well as psychosocial and social difficulties 3–7. Regarding the societal impact of substance abuse, these physical and psychological consequences cause substantial economic and social burdens, for example, early retirement 8 9.…”

Section: Introductionmentioning

confidence: 99%

Evaluating a rehabilitative intervention for substance-dependent patients with and without their accompanying children in Germany (KontextSucht): study protocol for a non-randomised trial

Stullich,

Hoffmann,

Stephan

et al. 2024

BMJ Open

View full text Add to dashboard Cite

IntroductionPeople suffering from substance use disorders often live in social contexts with children or are parents themselves. Addicted parents show specific substance-related problems while raising their children, which often leads to various lifelong consequences for the children. The German rehabilitative treatment system allows bringing children to inpatient treatment centres. This mixed-methods study evaluates a newly developed intervention, called ‘KontextSucht’ or ‘AddictionContext’, for parents in rehabilitation treatment centres concerning the effectiveness of the intervention in parenting and abstinence outcome.Methods and analysisThe study uses a two-stage parallel mixed-methods design. A feasibility study (stage 1) and a benefit assessment (stage 2) will be conducted to evaluate the intervention. Both parts of the study will be carried out with qualitative and quantitative work packages. German-speaking parents of children 0–14 years will be included in this study. Qualitative data will be analysed using qualitative content analyses, whereas quantitative data will be analysed descriptively using regression analysis as well as linear mixed models.Ethics and disseminationAll participants will receive detailed information on the study and sign informed consent before data collection. The research team has obtained the approval of the Ethical Review Committee at the Technical University of Munich in Germany and will follow all legislation rules regarding data protection. The study results will be published in peer-reviewed national and international journals. Furthermore, the study results will be included in an intervention manual distributed to treatment centres.Trial registration numberDRKS00030950.

show abstract

Infektionskrankheiten

Kapfhammer¹

2022

Depression, Angst, Traumatischer Stress Und Internistische Erkrankungen

View full text Add to dashboard Cite

Zur Komorbidität von Posttraumatischer Belastungsstörung und Sucht in biopsychosozialer Perspektive

Cited by 9 publications

References 204 publications

Coping motives mediate the relationship between PTSD and MDMA use in adolescents with substance use disorders

Coping motives mediate the relationship between PTSD and MDMA use in adolescents with substance use disorders

Evaluating a rehabilitative intervention for substance-dependent patients with and without their accompanying children in Germany (KontextSucht): study protocol for a non-randomised trial

Infektionskrankheiten

Contact Info

Product

Resources

About