Zur pathologischen Anatomie der Alarmreaktion nach Kerngiften

Klein, Hugh

doi:10.1007/bf00957204

Cited by 18 publications

(2 citation statements)

References 92 publications

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“…Those organs physiologically affected by colchicine intoxication have demonstrated corresponding morphological changes. Autopsy studies of colchicine‐toxic patients describe arrested mitoses in lymph nodes, spleen, colon, small intestine, stomach, oesophagus, kidney, urinary tract, respiratory tract and liver 6,9,11,19–22,27,28,36–39 . Arrested mitoses have also been described in colonic biopsies, 40 colonic polyps 41 and bone marrow aspirates 7 .…”

Section: Discussionmentioning

confidence: 99%

Toxic epidermal necrolysis-like reaction secondary to colchicine overdose

Arroyo¹,

Sanders²,

Yee³

et al. 2004

Br J Dermatol

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Section: Discussionmentioning

confidence: 99%

Toxic epidermal necrolysis-like reaction secondary to colchicine overdose

Arroyo¹,

Sanders²,

Yee³

et al. 2004

Br J Dermatol

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“…Zahlreiche kurzfristige mitotische Tag-Nacht-Periodizitäten wurden im Pflanzen reich [1][2][3][4][5][6][7][8][9], 73,84], 20,23,27,83] …”

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MITOSENPERIODIK IN DER NEBENNIERENRINDE, SCHILDDRüSE, IM DUODENAL- UND MUNDHöHLENEPITHEL DER RATTE

Mühlemann¹,

Marthaler²,

Rateitschak³

1956

Cells Tissues Organs

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Diurnal mitotic periodicity in regen erating rat liver

Jaffe

1954

Anat. Rec.

121

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TWO FIQURESI n 1952, an experiment was started concerned with the effects of x-radiation upon cell (division on regenerating rat livers. Groups of rats were partially hepatectomized and then irradiated a certain number of hours after the operations. Each group was sacrificed at 12-hour intervals following irradiation and the livers subsequently sectioned, stained, and examined. The average number of mitoses per unit volume of liver parenchyma, as compared with that of the non-irradiated controls, was used as the criterion of radiation effect. Initially, the partial hepatectomies, and, therefore, the radiation, were performed a t different hours of the day, so arranged that killing and autopsy were always carried out in the morning. To test the reliability of this procedure, two groups of animals, to be sacriiiced at the same time after radiation, were hepatectomized at reciprocal hours of the day -one group at 9 : 00-10 : 00 A.M., the other at 9 : 00-10 : 00 P.M.Except for the time difference, the general schedule followed was identical for both groups. It was noted at once that there was a wide gulf f;eparating the mean values recorded for each group. These results suggested the possibility that a diurnal periodicity in mitotic activity was responsible for thc discrepancy, and the experiment was redesigned so that all operations were carried out at the same hours, all time being reckoned thereafter from this Rhode Island.

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Zur pathologischen Anatomie der Alarmreaktion nach Kerngiften

Cited by 18 publications

References 92 publications

Toxic epidermal necrolysis-like reaction secondary to colchicine overdose

Toxic epidermal necrolysis-like reaction secondary to colchicine overdose

MITOSENPERIODIK IN DER NEBENNIERENRINDE, SCHILDDRüSE, IM DUODENAL- UND MUNDHöHLENEPITHEL DER RATTE

Diurnal mitotic periodicity in regen erating rat liver

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