Zur Pathomorphologie der akuten hypoxischen Knochenmarksschädigung

Hill, K.; Leuschner, U.; U, Semmler

doi:10.1007/bf01852248

Res. Exp. Med.

1973

DOI: 10.1007/bf01852248

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Zur Pathomorphologie der akuten hypoxischen Knochenmarksschädigung

K. Hill

U. Leuschner

Semmler U

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1973

1975

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Pathologisch-anatomische Befunde im Knochenmark des Menschen nach Schockzust�nden

Schubert

1975

Klin Wochenschr

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In a post mortem study of shock-induced changes in the bone marrow, marrow from six different parts of the skeletal system was examined in a total of 109 patients. The comparison of a group of 64 subjects deceased in shock conditions with a control group of 25 deceased without shock showed: In 76,6% of all patients with shock, fibrin networks were found in the sinus and perisinoidal interstice of bone marrow. This can be demonstrated abundantly in every fourth patient with shock. Microthrombi and emboli occluding vessels in the marrow were seen in only 6.3% of the shock cases (controls 0%). The different forms of fibrin precipitates appear most commonly after shock caused by infection. Platelet aggregates in the vessels are seen in 28.2% of all cases with shock (controls 8%). 5% of the cases with shock showed infarction-like necroses of the bone marrow and a further 23% necroses of small cell groups. In every fifth patient with shock, a great number of nucleated blood cells and their precursors were found in the marrow sinus (controls 8%). In a third group of 20 patients with serious illness alledgedly without shock, 45 per cent had a fibrin network when compared with the control group. When several of these findings are present simultaneously, one can apply the term "shock marrow".

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Pathologisch-anatomische Befunde im Knochenmark des Menschen nach Schockzust�nden

Schubert

1975

Klin Wochenschr

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Zur Pathomorphologie der akuten hypoxischen Knochenmarkschädigung

Leuschner

Hill

1973

Blut

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Repetitive blood-free marrow sampling

Tauber

1974

Journal of Immunological Methods

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Zur Pathomorphologie der akuten hypoxischen Knochenmarksschädigung

Cited by 3 publications

References 16 publications

Pathologisch-anatomische Befunde im Knochenmark des Menschen nach Schockzust�nden

Pathologisch-anatomische Befunde im Knochenmark des Menschen nach Schockzust�nden

Zur Pathomorphologie der akuten hypoxischen Knochenmarkschädigung

Repetitive blood-free marrow sampling

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