Zur Pathophysiologie der pulmonalen Hypertonie und des chronischen Cor pulmonale

Reindell, H; Doll, E; Steim, H; Bilger, R.; Gebhardt, W; Emmrich, J; Buechner, C; Schwilden, E.-D.

doi:10.1007/bf02144720

Cited by 23 publications

(2 citation statements)

References 74 publications

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“…As a compensatory mechanism in chronic pressure overlaod, concentric hypertrophy of the left and right ven tricle precedes dilation [26], Close correlation between right ventricular area considered separately and pulmo nary artery mean pressure is therefore not to be expected. Accordingly, a correlation between right ventricular area or area index and pulmonary artery mean pressure was less than that for the remaining échocardiographie param eters which take into account the area of the right atrium or the areas of both left heart cavities.…”

Section: Function and Compensation Mechanism In Right Ventricular Prementioning

confidence: 99%

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Two-Dimensional Echocardiographic Assessment of Right Cardiac Pressure Overload in Patients with Chronic Obstructive Airway Disease

Machraoui

Dryander²,

Hinrichsen³

et al. 1993

Respiration

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Two-dimensional echocardiography was used to estimate right cardiac pressure overload in patients with chronic obstructive airway disease. Area measurements of the four heart chambers were carried out from the apical four-chamber view. Additionally, the respiratory behaviour of the inferior vena cava was examined from the subcostal view. A good apical imaging of the four-chamber view for area measurement was obtained in 44 out of 48 patients with chronic obstructive airway disease. The respiratory behaviour of the inferior vena cava was investigated from the subcostal view in 38 patients. Within 8 days after echocardiography, right cardiac catheterization was carried out in order to measure pulmonary artery and right atrial mean pressures and to determine pulmonary vascular resistance. A good correlation was found between pulmonary artery mean pressure and the following echocardiographic parameters: area index (area/body surface) of the two right heart cavities (r = 0.83), right-to-left ventricular area ratio (r = 0.82) and right-to-left cardiac area ratio (ratio between the added areas of both right heart cavities on the one side and the added areas of both left heart cavities on the other; r = 0.82). Correlation between these parameters and pulmonary vascular resistance (r = 0.71, 0.66 and 0.71, respectively) and between the right atrial mean pressure and the right atrial area index was less close (r = 0.64). On the other hand, the respiratory behaviour of the inferior vena cava proved to be highly specific but not very sensitive in predicting a pathological right atrial pressure. The combination of area measurements with investigation of the respiratory behaviour of the inferior vena cava is a useful method for evaluating the long-term effect of right cardiac pressure overload in patients with chronic obstructive airway disease, who can otherwise only be investigated with difficulty.

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Section: Function and Compensation Mechanism In Right Ventricular Prementioning

confidence: 99%

“…Acute pressure stress, such as in pulmonary embolism, may lead to acute dilation in an unadapted right ventricle [33]. On the other hand, pressure stress developing gradually, as in broncho pulmonary disease, leads to initial concentric hypertrophy and only later to dilation [26,34].…”

Section: Function and Compensation Mechanism In Right Ventricular Prementioning

confidence: 99%