Zur Wirkung von Oestradiol und Progesteron auf die Porphyrinsynthese in Leberzellkulturen

Doss, M.

doi:10.1007/bf01725683

Cited by 5 publications

(2 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The studies of Granick (1966), Doss (1969) and of other authors suggest that oestrogens are porphyrogenic in chicken embryos. Repeatedly reproduced studies (Ippen, Aust & Goerz, 1972;Simon, Berk6 & Dobozy, 1973) with experimental porphyria after hexachlorobenzene administration in rats (with a latent or with a manifest form of the disease) have proved that oestrogens can aggravate liver disorders either by rapidly producing manifest porphyric changes or by worsening existing ones.…”

Section: Discussionmentioning

confidence: 91%

Oestrogen-induced familial porphyria cutanea tarda

Malina

Chlumský

1975

Br J Dermatol

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 91%

Oestrogen-induced familial porphyria cutanea tarda

Malina

Chlumský

1975

Br J Dermatol

View full text Add to dashboard Cite

show abstract

“…Earlier investigations revealed that porphyrin biosynthesis is enhanced by exogenous estradiol, progesteron or other steroids in liver cell cultures of chick embryos (Doss 1969). In healthy women an influence on coproporphyrin isomer composition with increase of isomer I by high dose hormonal oral contraceptives was reported (Koskelo, Eisalo and Toivonen 1966).…”

Section: Introdutionmentioning

confidence: 99%

Hormonal Oral Contraceptives, Urinary Porphyrin Excretion and Porphyrias

Groß

Daume

et al. 1995

Horm Metab Res

View full text Add to dashboard Cite

The influence of hormonal oral contraceptives on the urinary porphyrin excretion of 40 healthy females has been studied. Two different hormonal oral contraceptives (combinations of gestoden or desogestrel, respectively, and ethinylestradiol) were applied for half a year. In each case twenty women received one of these two combinations. Porphyrin precursors delta-aminolevulinic acid and porphobilinogen were normal in all subjects as well as the mean of uroporphyrin and coproporphyrin. One healthy female developed a mild secondary coproporphyrinuria. In this case coproporphyrin isomer I was slightly enhanced and isomer III slightly lowered. Furthermore it could be shown that three females with repeated premenstrual clinical expression of an acute hepatic porphyria (acute intermittent porphyria and hereditary coproporphyria) could be treated successfully with a hormonal oral contraceptive or other exogenous hormones to stabilize the latent, subclinical phase of the disease.

show abstract

Klinisch-experimentelle untersuchungen zur entstehung der porphyrien

Ippen

Aust

1972

Arch. Derm. Forsch.

View full text Add to dashboard Cite

Zur Wirkung von Oestradiol und Progesteron auf die Porphyrinsynthese in Leberzellkulturen

Cited by 5 publications

References 9 publications

Oestrogen-induced familial porphyria cutanea tarda

Oestrogen-induced familial porphyria cutanea tarda

Hormonal Oral Contraceptives, Urinary Porphyrin Excretion and Porphyrias

Klinisch-experimentelle untersuchungen zur entstehung der porphyrien

Contact Info

Product

Resources

About