Zwitterionic betaine transition from micelles to vesicles induced by cholesterol

Alenaizi, R.; Radiman, Shahidan; Rahman, Irman Abdul; Mohamed, Faizal K.P. Kunchi

doi:10.1016/j.molliq.2016.09.062

Cited by 5 publications

(1 citation statement)

References 51 publications

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“…Critical micelle concentration, CMC, of amphiphiles found in this study, especially for C 10 BetC 2 Cl and C 12 BetC 2 Cl, in aqueous solution calculated from the surface ten-sion at t = 25 • C is at the m range characteristic for typical ionic surfactants with the decyl or dodecyl moiety [4,17,26,31], such as for dodecyltrimethylammonium bromide (15.3 ± 0.1 mmol•kg −3 ) [32], or at least about one order higher than for N-alkyl betaines (170-1.8 mmol•dm −3 ) [33,34], or one-third higher than for the equivalent surfactant sodium dodecyl sulfate, SDS (8 mmol•dm −3 ) [35]. For dodecyl betaine, C 12 Bet, the CMC at t = 10 • C is 2 mmol•dm −3 and increases with the temperature until it reaches 2.8 mmol•dm −3 at t = 57 • C, which is not so clear for amphiphiles [36].…”

Section: Surface Propertiesmentioning

confidence: 94%

A Study of the Micellar Formation of N-Alkyl Betaine Ethyl Ester Chlorides Based on the Physicochemical Properties of Their Aqueous Solutions

Geppert-Rybczyńska,

Mrozek-Wilczkiewicz,

Rawicka

et al. 2024

Molecules

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In this study, a series of four surface-active compounds—N-alkyl betaine ethyl ester chlorides, CnBetC2Cl—were synthesized and characterized in aqueous solutions. As with other alkyl betaines, these amphiphiles can be practically used, for example, as co-surfactants and/or solubility enhancers acting according to hydrotropic or micellar mechanisms, depending on the alkyl chain length in the amine. We focused on the representatives of the medium alkyl chain length (C6–C12) to find the dependence between the alkyl chain length in N-alkyl betaine ethyl ester chlorides and the surface, volumetric, acoustic, and viscometric properties of their solutions. Ethyl esters, the derivatives of amino acids, were chosen to increase functionality and take advantage of possible hydrolysis in solutions at higher pH, which is also a key parameter in biodegradability. The micellization parameters were calculated based on the physicochemical characteristics. We focused our interest on the ester with a dodecyl substituent since we can compare and discuss its properties with some other C12 representatives that are available in literature. Surprisingly, its micellization characteristic is almost temperature-independent in the investigated temperature range, t = (15–45) °C. Particularly interesting are the results of dynamic light scattering (DLS), which show that the changes in physicochemical parameters of the C12 homolog around the CMC are caused by the two types of micelles of different sizes present in solutions.

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