α‐Fe₂O₃@Ag and Fe₃O₄@Ag Core‐Shell Nanoparticles: Green Synthesis, Magnetic Properties and Cytotoxic Performance

Abstract

This work provides the synthetic route for the arrangement of Fe 3 O 4 @Ag and α-Fe 2 O 3 @Ag core-shell nanoparticles (NPs) with cytotoxic capabilities. The production of Fe 3 O 4 @Ag and α-Fe 2 O 3 @Ag core-shell NPs was facilitated utilizing S. persica bark extracts. The results of Powder X-ray Diffraction (PXRD), Ultraviolet-visible (UV-Vis) spectroscopy, Vibrating Sample Magnetometry (VSM), Energy Dispersive X-ray (EDX) analysis, Field Emission Scanning Electron Microscopy (FESEM), and Transmission Electron Microscopy (TEM) supported the green synthesis and characterization of Fe 3 O 4 @Ag and α-Fe 2 O 3 @Ag NPs. The particle size was measured by the TEM analysis to be about 30 and 50 nm, respectively; while the results of FESEM showed that α-Fe 2 O 3 @Ag and Fe 3 O 4 @Ag particles contained multi-faceted particles with a size of 50-60 nm and 20-25 nm, respectively. The outcomes of VSM were indicative of a saturation magnetization of 37 and 0.18 emu/g at room temperature, respectively. The potential cytotoxicity of the synthesized core-shell nanoparticles towards breast cancer (MCF-7) and human umbilical vein endothelial (HUVEC) cells was evaluated by an MTT assay. α-Fe 2 O 3 @Ag NPs were able to destroy 100 % of MCF-7 cell at doses above 80 μg/mL, and it was confirmed that Fe 3 O 4 @Ag NPs at a volume of 160 μg/mL can destroy 90 % of MCF-7 cells. Thus, the applicability of the prepared nanoparticles of these nanoparticles in biological and medical fields has been demonstrated.

Syzygium aromaticum Bud Extracted Core–Shell Ag–Fe Bimetallic Nanoparticles: Phytotoxic, Antioxidant, Insecticidal, and Antibacterial Properties

“…Further, the full masking of the absorption band of Ag NPs and the damping in peak confirms the successful creation of core-shell Ag-Fe BMNPs, showing that Ag NPs are acting as the core, covered by Fe NPs as the shell. Similar results have been reported earlier in diverse types of BMNPs [39].…”

“…are acting as the core, covered by Fe NPs as the shell. Similar results have been reported earlier in diverse types of BMNPs [39]. The reduction potential of metal ions contributes to the fabrication of such type of structure.…”

“…The metal ions present in metal's salt solution, having the greater reduction potential, possess the greater speed of reduction and, consequently, will reduce first and form the core, next to which the reduction of metal ions, having lesser reductional potential, occurs, which will develop the shell on the outer surface of the core. In the case of Ag-Fe core-shell BMNPs, the reduction potential of Ag is +0.80 V, and that of Fe is −0.04 V. So, Ag +1 ions were reduced first by biomolecules present in the SA extract, resulting in the core of Ag NPs, followed by the reduction of Fe +3 , forming the shell of Fe NPs [39,40]. In the case of heterogeneous materials, two absorption bands are formed.…”

Biosynthesis of ZnO, Bi2O3 and ZnO−Bi2O3 bimetallic nanoparticles and their cytotoxic and antibacterial effects

“… [9] Researchers are using the newly discovered nanoparticles to develop new treatments which including new properties for medical science. [ 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 ] Nanoparticles promote co‐administration, therapy and multimodal delivery (combination of therapy and diagnosis). The energy absorption and reflection properties of nanoparticles also enable them to improve the application of slow laser burns and hyperthermia, which can damage diseased tissues.…”

Green, Eco-Friendly, Highly Biocompatible and Bioactive Nanocomposite-Based Biopolymers Loaded with ZnO@Fe3O4 Nanoparticles

“…On the other hand, the use of Fe 3 O 4 nanoparticles in several novel fields will be highlighted, including energy storage, biosensing, environmental applications for the removal of heavy metals and organic pollutants, moreover it is use in development of magnetic resonance imaging (MRI) contrast agents, as well as antimicrobial and anticancer drug delivery agents with a good biosafety profile [17,18]. Moreover, Fe 3 O 4 nanoparticles are characterized by unique physicochemical properties, such as those of magnetic and electrical properties [19].…”