β-Aminoisobutyric Acid (α-Methyl-β-Alanine): A New Amino-Acid Obtained from Human Urine

ENANTIOPURE R(-)-3-AMINOISOBUTYRIC ACID SYNTHESIS USING Pseudomonas aeruginosa AS ENANTIOSPECIFIC BIOCATALYST

“…The product characterization is described below. Its absolute configuration was confirmed by polarimetry, corresponding to the value found in the literature (Crumpler et al, 1951). The enantiomeric excess was determined to be higher than 98%.…”

Amino Acid Metabolism in Infectious Hepatitis1

“…In addition, many of the essential amino acids were seen in the urine of a number of these patients. These included moderate increases of isoleucine/leucine, lysine, and (27) and hence this substance cannot be evaluated in the present study.…”

SOME GENETICAL AND ANTHROPOLOGICAL CONSIDERATIONS OF URINARY <i>β</i>-AMINOISOBUTYRIC ACID EXCRETION

“…R ather it seems th a t a specific difference in the kidney tubular reabsorption mechanism for this amino acid is responsible. This hypothesis was origi nally suggested by Crumpler, Dent, Harris and Westall [1951] and was based on paper chrom atographic studies of plasm a amino acids which revealed no difference between high and low excretors of BA IB with respect to plasm a BA IB concentration. However, actual plasm a levels of BAIB were not reported by these workers, presum ably because of the difficulty in quantifying by paper chrom atographic techniques substances in such low concentration as plasm a BAIB m ust be.…”

“…/Lam inoisobutyric acid (BAIB) was first detected in hum an urine by Crumpler, Dent, Harris and Westall [1951] and independently by F ink [1951]. It was observed th a t this non-protein amino acid was ex creted in urine in widely varying concentrations from person to person, bu t at a relatively constant rate for any one individual.…”