2009
DOI: 10.1002/bmb.20324
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β‐Lactamases in the biochemistry and molecular biology laboratory

Abstract: Abstractβ‐lactamases are hydrolytic enzymes that inactivate the β‐lactam ring of antibiotics such as penicillins and cephalosporins. The major diversity of studies carried out until now have mainly focused on the characterization of β‐lactamases recovered among clinical isolates of Gram‐positive staphylococci and Gram‐negative enterobacteria, amongst others. However, only some studies refer to the detection and development of β‐lactamases carriers in healthy humans, sick animals, or even in strains isolated fr… Show more

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Cited by 3 publications
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“…In Portugal, several studies have been conducted in order to describe the epidemiology, prevalence, and emerging spread of variants, in particular the β-lactamase-producing strains with possibility of resistance. Several Portuguese regions, such as the north and central, have been targeted by these studies [7,9,18,30,31,32,33]. However, due to constant epidemiological changes and to the absence of studies in other regions, this purpose has not yet been completely achieved.…”
Section: Introductionmentioning
confidence: 99%
“…In Portugal, several studies have been conducted in order to describe the epidemiology, prevalence, and emerging spread of variants, in particular the β-lactamase-producing strains with possibility of resistance. Several Portuguese regions, such as the north and central, have been targeted by these studies [7,9,18,30,31,32,33]. However, due to constant epidemiological changes and to the absence of studies in other regions, this purpose has not yet been completely achieved.…”
Section: Introductionmentioning
confidence: 99%