β-TCP scaffold coated with PCL as biodegradable materials for dental applications

Shi, Yunzhi; Liu, Jing; Yu, Lingmin; Zhong, Li Zhen; Jiang, Heng Bo

doi:10.1016/j.ceramint.2018.05.142

Cited by 27 publications

(15 citation statements)

References 34 publications

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“…This section will be focused on composites that combine ceramics and polymers, and despite recognizing that the resulting composite scaffolds can be obtained by mixing ceramic powder with a polymer solution and using different manufacturing techniques [ 17 , 105 , 106 ], by depositing ceramics onto polymers [ 17 , 107 , 108 ], or by the deposition of polymers onto ceramics [ 17 , 109 , 110 , 111 , 112 , 113 ], only the last one will be reviewed here.…”

Section: Bone Tissue Engineeringmentioning

confidence: 99%

“…In addition, there was a decrease in the degradation rate of the majority of the coatings, and a consequent positive impact on the evolution of their mechanical properties. Shi et al [ 113 ] produced a β-TCP scaffold through the polymeric sponge replication method and aimed to improve the mechanical properties of the scaffolds by coating them with PCL. It was observed that PCL addition significantly improved the compressive and bending strength, with the highest value being registered for the scaffolds containing 40% of β-TCP and 5% of PCL.…”

Section: Bone Tissue Engineeringmentioning

confidence: 99%

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Synthetic and Marine-Derived Porous Scaffolds for Bone Tissue Engineering

Neto

Ferreira

2018

Materials

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Bone is a vascularized and connective tissue. The cortical bone is the main part responsible for the support and protection of the remaining systems and organs of the body. The trabecular spongy bone serves as the storage of ions and bone marrow. As a dynamic tissue, bone is in a constant remodelling process to adapt to the mechanical demands and to repair small lesions that may occur. Nevertheless, due to the increased incidence of bone disorders, the need for bone grafts has been growing over the past decades and the development of an ideal bone graft with optimal properties remains a clinical challenge. This review addresses the bone properties (morphology, composition, and their repair and regeneration capacity) and puts the focus on the potential strategies for developing bone repair and regeneration materials. It describes the requirements for designing a suitable scaffold material, types of materials (polymers, ceramics, and composites), and techniques to obtain the porous structures (additive manufacturing techniques like robocasting or derived from marine skeletons) for bone tissue engineering applications. Overall, the main objective of this review is to gather the knowledge on the materials and methods used for the production of scaffolds for bone tissue engineering and to highlight the potential of natural porous structures such as marine skeletons as promising alternative bone graft substitute materials without any further mineralogical changes, or after partial or total transformation into calcium phosphate.

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Section: Bone Tissue Engineeringmentioning

confidence: 99%

Section: Bone Tissue Engineeringmentioning

confidence: 99%

Synthetic and Marine-Derived Porous Scaffolds for Bone Tissue Engineering

Neto

Ferreira

2018

Materials

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“…After fulfilling their function, they are cleared out of the body by natural methods. Synthetic, biodegradable polymers are used to produce surgical sutures [2,3], bone anastomosis plates [4], materials for tissue scaffolds [5,6,7], and scaffolds for repairing tendons and ligaments [8].…”

Section: Introductionmentioning

confidence: 99%

One Year Evaluation of Material Properties Changes of Polylactide Parts in Various Hydrolytic Degradation Conditions

Andrzejewska

2019

Polymers

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Biodegradable biocompatible materials are widely used in medical applications. Determining the possibility of using biodegradable materials depends on determining the changes in their parameters over time due to degradation. The current scientific research on biodegradable materials has presented results based on research methods characterized by the different geometry and cross-section size of the specimen, type of degradation medium, or different pH value of the medium or maximum degradation time. This paper presents the results of a one-year study on the influence of the type of degradation medium on the changes in mechanical behavior and the uptake of the degradation medium by biodegradable specimens with large cross-sections. In addition, a prototype of a test stand was created, which allowed for the specimens to be stored vertically to ensure regular medium exposure and eliminate the interaction of the surface of the tested specimens with the sides of the container. The obtained results allowed the statistical significance of differences in the mechanical parameters determined in the uniaxial tensile test after 2, 4, 6, 12, 26, 39, and 52 weeks of degradation to be indicated depending on the type of degradation medium. It was proven that the changes in mechanical behavior depend on the percentage change in the mass of the specimens during degradation. The percentage change in mass depends on the type of degradation medium. Based on the results of this research, it was noted that in long-term degradation above 12 weeks, buffered sodium chloride solution is the optimal choice for the degradation medium. However, distilled water or physiological saline solution can be used as an alternative during the degradation period for up to 12 weeks.

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“…In addition, in the majority of the coatings, there was a decrease in degradation rate having a positive impact on the evolution of their mechanical properties. Shi et al [109] produced a -TCP scaffold through the polymeric sponge replication method and aimed to improve the mechanical properties of the scaffolds by PCL addition. It was observed that the addition of PCL significantly improved the compressive and bending strength and the highest value was registered with the scaffolds containing 40% of -TCP and 5% of PCL.…”

Section: Composite Materialsmentioning

confidence: 99%

“…With this in mind, composite materials have been widely explored in bone tissue engineering field since it combines two different materials that resulted in an improvement in mechanical properties and osteoconductive properties of bone grafts. This review will be focused on composites that combine ceramic and polymer materials and despite recognizing that these composite scaffolds can be obtained by mixing ceramic powder with a polymer solution and using different manufacturing techniques [17,101,102], ceramic deposition onto polymers [17,103,104] or by polymer deposition onto ceramics [17,[105][106][107][108][109], only the last one will be reviewed.…”

Section: Composite Materialsmentioning

confidence: 99%

Synthetic and Marine-Derived Porous Bone Graft Substitutes

Neto¹,

Ferreira²

2018

Preprint

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Bone is a dynamic tissue with the capacity of repair and regeneration in specific conditions. Nevertheless, due to the increased incidence of bone disorders, the need of bone grafts has been growing over the past decades and the development of a bone graft with optimal properties remains a clinical challenge. This review addresses the bone properties (morphology, composition and their repair and regeneration capacity) and then is focused on the potential strategies for bone repair and regeneration. It describes the requirements for designing a suitable scaffold material, types of materials (polymers, ceramics and composites) and techniques to obtain the porous structures (additive manufacturing techniques/robocasting or derived from marine skeletons) for bone tissue engineering applications. The main objective of this review is to gather the knowledge on the materials and methods for the production of scaffolds for bone tissue engineering and highlight that natural materials, namely the marine skeletons represent a promising alternative.

show abstract

β-TCP scaffold coated with PCL as biodegradable materials for dental applications

Cited by 27 publications

References 34 publications

Synthetic and Marine-Derived Porous Scaffolds for Bone Tissue Engineering

Synthetic and Marine-Derived Porous Scaffolds for Bone Tissue Engineering

One Year Evaluation of Material Properties Changes of Polylactide Parts in Various Hydrolytic Degradation Conditions

Synthetic and Marine-Derived Porous Bone Graft Substitutes

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