γ-Aminobutyric acid (GABA) regulates lipid production and cadmium uptake by Monoraphidium sp. QLY-1 under cadmium stress

Zhao, Yongteng; Song, Xueting; Zhong, Du-bo; Yu, Lei; Yu, Xuya

doi:10.1016/j.biortech.2019.122500

Cited by 57 publications

(21 citation statements)

References 49 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…QLY-1 where GABA application was reported to increase the biomass production under Cd stress. 18 The reduced cell growth and biomass production in T. subcordiformis exposed to GABA also differed from the higher plants such as maize for which exogenous GABA application improved seedling growth in terms of seedling length and biomass accumulation under normal conditions. 22 Therefore, GABA might play a different role on cell growth in the microalga T. subcordiformis compared to other microalgae and higher plants.…”

Section: Cell Growth and Starchmentioning

confidence: 97%

“…QLY-1 for which GABA treatment was shown to facilitate starch degradation by upregulating αamylase activity under Cd stress. 18 In addition, GABA was also demonstrated to promote the α-amylase activity and facilitate seed starch degradation in barley with a dose-responsive effect. 24 Collectively, it appeared that exogenous GABA supply exhibited unique effects on this starch-producing microalga against other microalgae or higher plants in terms of starch metabolism.…”

Section: Cell Growth and Starchmentioning

confidence: 99%

“…QLY-1 in which exogenous GABA addition was shown to increase biomass and lipid production under cadmium (Cd) stress. 18 The application of GABA for enhancing microalgal starch production needs intensive investigation.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Enhancing Photosynthetic Starch Production by γ-Aminobutyric Acid Addition in a Marine Green Microalga Tetraselmis subcordiformis under Nitrogen Stress

Ran

Pan

et al. 2020

Ind. Eng. Chem. Res.

View full text Add to dashboard Cite

Microalgal starch, a potential feedstock for renewable fuels and chemicals, is usually induced under stress, which hinders the simultaneous enhancement of starch content and yield. This study applied γ-aminobutyric acid (GABA) to modulate cell metabolism for improving photosynthetic starch production in microalga Tetraselmis subcordiformis under nitrogen limitation (±N) and depletion (−N). Under ±N, 2.5 mM GABA abated nitrogen metabolism but enhanced starch content by 27% with an uncompromised starch yield due to the moderate inhibition of cell growth and elevated photoprotection. Under −N, 10 mM GABA entitled improved stress tolerance and enhanced starch content by 23.4% with a simultaneous 28.6% promotion of starch yield. The maximum starch content and yield under this condition reached 69.0% DW and 1.84 g L −1 , respectively, which represented the highest starch levels in this microalga and exceeded most of the starch production performance among the microalgae reported. GABA addition was promising to improve microalgal starch production.

show abstract

Section: Cell Growth and Starchmentioning

confidence: 97%

Section: Cell Growth and Starchmentioning

confidence: 99%

See 1 more Smart Citation

Enhancing Photosynthetic Starch Production by γ-Aminobutyric Acid Addition in a Marine Green Microalga Tetraselmis subcordiformis under Nitrogen Stress

Ran

Pan

et al. 2020

Ind. Eng. Chem. Res.

View full text Add to dashboard Cite

show abstract

“…Although glycerol, okara, and corn steep liquor are considered as byproducts, they are nutrient rich. However, they are highly underused energy sources, as a large proportion is dumped into incinerators and landfills ( Lee et al, 2019 ; Kang et al, 2020 ; Zhao et al, 2020 ).…”

Section: Introductionmentioning

confidence: 99%

Engineering Sphingobium sp. to Accumulate Various Carotenoids Using Agro-Industrial Byproducts

Liu

Yang

et al. 2021

Front. Bioeng. Biotechnol.

View full text Add to dashboard Cite

Carotenoids represent the most abundant lipid-soluble phytochemicals that have been shown to exhibit benefits for nutrition and health. The production of natural carotenoids is not yet cost effective to compete with chemically synthetic ones. Therefore, the demand for natural carotenoids and improved efficiency of carotenoid biosynthesis has driven the investigation of metabolic engineering of native carotenoid producers. In this study, a new Sphingobium sp. was isolated, and it was found that it could use a variety of agro-industrial byproducts like soybean meal, okara, and corn steep liquor to accumulate large amounts of nostoxanthin. Then we tailored it into three mutated strains that instead specifically accumulated ∼5 mg/g of CDW of phytoene, lycopene, and zeaxanthin due to the loss-of-function of the specific enzyme. A high-efficiency targeted engineering carotenoid synthesis platform was constructed in Escherichia coli for identifying the functional roles of candidate genes of carotenoid biosynthetic pathway in Sphingobium sp. To further prolong the metabolic pathway, we engineered the Sphingobium sp. to produce high-titer astaxanthin (10 mg/g of DCW) through balance in the key enzymes β-carotene ketolase (BKT) and β-carotene hydroxylase (CHY). Our study provided more biosynthesis components for bioengineering of carotenoids and highlights the potential of the industrially important bacterium for production of various natural carotenoids.

show abstract

“…Food crops, such as grain legumes, which are commonly grown in rainfed areas, are more prone to drought stress; The worldwide climate models have predicted continuous variability and rise in the intensity and frequency of drought incidents (Rosenzweig and Hillel 2005;Sehgal et al 2019). The deficiency of accessible water restrains plant productivity owing to drought-induced cellular membrane damage, nutritional imbalance, and metabolic disorders (Zhao et al 2020). Yong et al (2017), stated that the exogenous application of GABA is an effective approach to improve the drought stress form plants.…”

Section: Gaba and Drought Stressmentioning

confidence: 99%

Role of Gamma Amino Butyric Acid (GABA) against abiotic stress tolerance in legumes: a review

Sita

Kumar²

2020

Plant Physiol. Rep.

View full text Add to dashboard Cite

Legumes are well known for their nutritional and health benefits as well as for their impact in the sustainability of agricultural systems. Under current scenarios threatened by climate change highlights the necessity for concerted research approaches in order to develop crops that are able to cope up with environmental challenges. Various abiotic stresses such as cold, heat, drought, salt, and heavy metal induce a variety of negative effects in plant growth, development and significantly decline yield and quality. Plant growth regulators or natural products of plants are reported to be effective to improve plant tolerance to several abiotic stresses. Gamma Amino Butyric Acid (GABA) is a non-protein amino acid involved in various metabolic processes, and partially protects plants from abiotic stress. GABA appears to impart partial protection to various abiotic stresses in most plants by increasing leaf turgor, increased osmolytes and reduced oxidative damage by stimulation of antioxidants. We have compiled various scientific reports on the role and mechanism of GABA in plants against coping with various environmental stresses. We have also described the emerging information about the metabolic and signaling roles of GABA which is being used to improve legume crop against abiotic stress.

show abstract

γ-Aminobutyric acid (GABA) regulates lipid production and cadmium uptake by Monoraphidium sp. QLY-1 under cadmium stress

Cited by 57 publications

References 49 publications

Enhancing Photosynthetic Starch Production by γ-Aminobutyric Acid Addition in a Marine Green Microalga Tetraselmis subcordiformis under Nitrogen Stress

Enhancing Photosynthetic Starch Production by γ-Aminobutyric Acid Addition in a Marine Green Microalga Tetraselmis subcordiformis under Nitrogen Stress

Engineering Sphingobium sp. to Accumulate Various Carotenoids Using Agro-Industrial Byproducts

Role of Gamma Amino Butyric Acid (GABA) against abiotic stress tolerance in legumes: a review

Contact Info

Product

Resources

About