δ-Storage pool disease: a pitfall in the forensic investigation of sudden anal blood loss in children: a case report

Abstract

We present the case of a 3.5-year-old boy with sudden anal blood loss at school. Sexual abuse was suspected, and, apart from anal fissures seen on sigmoidoscopy, no other clinical signs of any sort of disorder were present. As no medical explanation for the blood loss could be given, penetrating anal trauma was suggested. During follow-up consultations, there were complaints of occasional blood loss. Platelet aggregation tests and electron microscopy finally helped diagnose a delta-storage pool disease which is a rare haemostatic disorder involving the dense granules of the platelets. Although exclusion of well-known blood diseases through routine laboratory testing is a common practice in children with sudden blood loss, this case illustrates the value of more specialised investigation both from a diagnostic and forensic point of view.

A new autosomal STR nineplex for canine identification and parentage testing

“…The importance of this species for research on genetic diseases urged the production of a highquality complete genome sequence, publicly available since 2004 [2][3][4]. Dogs are also increasingly reported in forensic caseworks involving accidents, dog attacks or the analysis of canine biological evidence that can help in the identification of a human perpetrator [5][6][7][8] as ''silent witnesses'' [9].…”