In the framework of a multiphase transport model, fluctuation and correlation of the azimuthal anisotropies in 12 C + 197 Au collisions at √ S NN = 200 GeV are explored. Properties of the initial eccentricity and final harmonic flow fluctuation resulted from 12 C + 197 Au collisions with Woods-Saxon configuration and triangular α-clustering configurations of 12 C are investigated via scaled variance, skewness, and kurtosis. Comparisons are made between results from α-clustered configurations and Woods-Saxon configuration. The triangular flow fluctuation is found to have particular sensitivity in distinguishing triangular α-clustering structure of 12 C. Furthermore, correlations between initial eccentricities and final flow harmonics are studied with strong multiplicity dependence observed for the correlation functions.