Биологическая Активность Адамантансодержащих Моно- И Полициклических Пиримидиновых Производных (Обзор)

Shokova, E. A.; Ковалев, В. В.

doi:10.30906/0023-1134-2016-50-2-3-15

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Cited by 4 publications

(1 citation statement)

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“…С той же целью авторами синтезированы адамансодержащие моно-и полициклические пиримидиновые производные [5], а также серия 5-(арилметилен) гексагидропиримидин-2,4,6-трионов [6].…”

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Reactions of 5-amino-4-substituted-6-Mercaptopyrimidines with Halogencarboxylic Acid Chlorides

Keremov¹

2020

HDSU

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Reactions of 5-amino-4-substituted-6-Mercaptopyrimidines with Halogencarboxylic Acid Chlorides

Keremov¹

2020

HDSU

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Chemical transformations of 3-bromoethyl-5,7-dimethyl2-oxaadamantan-1-ol in sulfuric acid

Ivleva,

Simatova,

Zaborskaya

et al. 2023

Žurnal organičeskoj himii

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The reactions of 3-bromomethyl-5,7-dimethyl-2-oxaadamantan-1-ol in a 96% acid medium both in the presence and in the absence of nucleophiles were studied. During the reactions a number of structural transformations of the 2-oxaadamantane cage take place. The possibility of obtaining 1,2,3-trisubstituted adamantanes is also presented. The structural features of new compounds are investigated using 2D NMR spectroscopy and XRD analysis. The obtained compounds can be used in the directed synthesis of a new cage heterocycles for studying of biological activity.

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Synthesis and chemical transformations of 1-aryladamantanes

Ivleva,

Orlinsky,

Zaborskaya

et al. 2023

Žurnal organičeskoj himii

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The synthesis was carried out and the transformations of 1-aryladamantanes in fuming nitric acid were studied. The reactions include nitroxylation of saturated cage and nitration of the aromatic moiety and lead to 3-(dinitroaryl)-1-adamantylnitrates. A number of new polyfunctional compounds have been synthesized based on reactions of substituted 3-(dinitroaryl)-1-adamantyl nitrates with nucleophiles in concentrated sulfuric acid. Due to the multifunctionality, the obtained compounds can be used as starting materials in the synthesis of substances with a wide spectrum of biological activity and materials with a complex of valuable properties.

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Биологическая Активность Адамантансодержащих Моно- И Полициклических Пиримидиновых Производных (Обзор)

Cited by 4 publications

References 34 publications

Reactions of 5-amino-4-substituted-6-Mercaptopyrimidines with Halogencarboxylic Acid Chlorides

Reactions of 5-amino-4-substituted-6-Mercaptopyrimidines with Halogencarboxylic Acid Chlorides

Chemical transformations of 3-bromoethyl-5,7-dimethyl2-oxaadamantan-1-ol in sulfuric acid

Synthesis and chemical transformations of 1-aryladamantanes

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