К Вопросу Об Этиологии И Прогнозе Неразвивающейся Беременности

Abstract

This article provides a review of domestic and international sources on the issue of non-developing pregnancy (NDP), which is a common yet poorly understood cause of early recurrent pregnancy loss. The review highlights contemporary aspects of NDP etiology, identifying key factors contributing to its development, including endocrine and immunological disorders in the mother, chronic endometritis, chromosomal anomalies, infectious factors (including sexually transmitted infections), genetic mutations, and uterine developmental abnormalities. The role of the immune and endocrine systems in the pathogenesis of NDP is described. The wide range of risk factors and the potential for predicting this pathology necessitate further investigation. Insufficient consideration of possible etiological factors and conditions leading to NDP increases the risk of recurrent reproductive losses. The diagnosis of the causes of non-developing pregnancy plays a crucial role in determining therapeutic tactics and approaches for the subsequent management of the couple, thereby enhancing the chances of a favorable outcome in future pregnancies.