Методы Получения Поляризованного Ксенона Для Магнитно-Резонансной Томографии (Обзор)

Григорьев, Г.Ю.; Лагутин, А.С.

doi:10.21883/jtf.2022.09.52919.65-22

Cited by 2 publications

(1 citation statement)

References 62 publications

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“…В частности, при определении стадии РМП до начала лечения в 10-20 % случаев имеют место завышение или недооценка. Также может не оправдаться ожидаемый прогноз эффективности лечения [3][4][5]. Так или иначе, для возможности прогнозирования эффективности химиотерапии необходимо иметь минимум две контрольные точки для визуализации опухоли: до и после лечения.…”

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Volumetric tumor segmentation according to diffusion-weighted MRI data in predicting and evaluating the response to chemotherapy in bladder cancer

et al. 2023

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The purpose of the study was to develop and evaluate the technique for volumetric tumor segmentation based on diffusion-weighted magnetic resonance imaging (DW-MRI) in predicting and assessing the response to chemotherapy in patients with bladder cancer (BC). Material and Methods. We examined 26 patients with morphologically verified transitional cell carcinoma of the bladder. The group was characterized by the presence of one or several tumors with a size of 17 to 46 mm. Before planning chemotherapy according to the M-VAC scheme, a study and post-processing of DW-MRI with volumetric segmentation of lesions, assessment of the volume and apparent diffusion coefficient (ADC) in the entire tumor mass were performed. According to the ADC data, shape of the tumor and its relation to the bladder wall, the coefficient (C) for predicting the response to chemotherapy was calculated. Results. In the cases with a coefficient value below 0.51, a high risk of treatment failure was predicted, at C≥0.74, a positive effect of treatment was predicted. With a value of 0.51≤C<0.74, the prognosis was uncertain, stabilization was more likely. The sensitivity and specificity of the method were 92.3 % and 92.4 %, respectively. Conclusion. The method of volumetric segmentation makes it possible to predict and evaluate bladder cancer response to chemotherapy with a sufficiently high accuracy. The advantages of the method are the possibility of assessing the tumor regardless of the degree of filling of the bladder, with non-contrast MRI, and with large lesions.

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Section: Introductionunclassified

Volumetric tumor segmentation according to diffusion-weighted MRI data in predicting and evaluating the response to chemotherapy in bladder cancer

et al. 2023

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Optical pumping of rubidium isotopes by Cr3+:BeAl2O4 laser radiation

Antipov,

Putilov,

Shepelev

2023

Izvestiâ Akademii nauk SSSR. Seriâ fizičeskaâ

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We consider the use of a Cr3+:BeAl2O4 laser in free-running operating as a source of emission for optical pumping rubidium alkali metal vapors. The use of dispersive elements in the composition of the laser cavity makes it possible to smoothly tune lasing wavelength and to realize generation at wavelengths corresponding to the D1 and D2 lines of the 85Rb and 87Rb isotopes. Optical pumping of rubidium isotopes by laser emission with wavelengths of 795 and 780 nm, respectively, is experimentally implemented, and their fluorescence is demonstrated. The question of using a wavelength-tunable laser in the method of spin-exchange optical pumping of noble gases is discussed.

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Методы Получения Поляризованного Ксенона Для Магнитно-Резонансной Томографии (Обзор)

Cited by 2 publications

References 62 publications

Volumetric tumor segmentation according to diffusion-weighted MRI data in predicting and evaluating the response to chemotherapy in bladder cancer

Volumetric tumor segmentation according to diffusion-weighted MRI data in predicting and evaluating the response to chemotherapy in bladder cancer

Optical pumping of rubidium isotopes by Cr<sup>3+</sup>:BeAl<sub>2</sub>O<sub>4</sub> laser radiation

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