Мультисистемный Воспалительный Синдром, Ассоциированный С Covid-19 У Детей, Как Исход Легких Форм Заболевания

Мелехина, Е.В.; Музыка, А.Д.; Nikolaeva, S.V.; Usenko, D.V.; Понежева, Ж.Б.; Мирзонов, Владислав; Barykin, V.I.; Novikov, D.E.; Gorelov, А.V.

doi:10.21055/preprints-3111890

Cited by 2 publications

(2 citation statements)

References 21 publications

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“…In co-infection, herpes zoster reactivation is known to be the main marker of COVID-19, there is a synergy between both viruses causing immune status abnormalities in patients [35]. The description of some clinical cases in children mentions possible reactivation of herpesvirus infections associated with SARS-CoV-2 [36]. A retrospective analysis of stool samples from children admitted to an infectious disease hospital with acute enteric infection is reported.…”

Section: Resultsmentioning

confidence: 99%

Current Aspects of the Clinical Course of Covid-19 in Children. Clinical Cases

Kamalova

2023

appmed

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In the pediatric population, coronavirus infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is more commonly observed in asymptomatic and moderately symptomatic cases. However, when COVID-19 coexists with other infections, it can result in a more severe disease progression. Various subtypes of the SARS-CoV-2 virus are associated with different clinical presentations, with certain subtypes exhibiting a predominance of specific symptoms or manifestations. Clinical manifestations of COVID-19 in children, both during the acute phase of the disease and in the post-COVID-19 period, are not fully understood and different compared to adults. This article presents four clinical cases in which PCR-confirmed COVID-19 was observed in combination with infections caused by viruses such as Ebstein-Barr, varicella, and rotavirus. The severity of the disease in these cases was attributed to symptoms related to intoxication, as well as skin and intestinal syndromes. To understand important genomic signatures of SARS-CoV-2 virus circulating in the area, the genome-wide sequencing was performed for the SARS-CoV-2 samples isolated from nasopharyngeal swabs collected from four patients.Based on the genotyping results, all four samples were found belonging to the SARS-CoV-2 virus Omicron lineage. Three months after the initial testing, follow-up evaluations of the children indicated a higher likelihood of complete recovery. However, some underlying disease manifestations, including anemia and atopic dermatitis, persisted despite the resolution of COVID-19 symptoms.

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Section: Resultsmentioning

confidence: 99%

Current Aspects of the Clinical Course of Covid-19 in Children. Clinical Cases

Kamalova

2023

appmed

View full text Add to dashboard Cite

show abstract

“…In co-infection, herpes zoster reactivation is known to be the main marker of COVID-19, there is a synergy between both viruses causing immune status abnormalities in patients [36]. The description of some clinical cases in children mentions possible reactivation of herpesvirus infections associated with SARS-CoV-2 [37]. A retrospective analysis of stool samples from children admitted to an infectious disease hospital with acute enteric infection is reported.…”

Section: Clinical Cases Treatment and Follow-up In The Post-covid Periodmentioning

confidence: 99%

Co-Infection With Covid-19 and Genetic Diversity of Sars-Cov-2 in Children

Kamalova,

Makibayeva,

Amirgazin

et al. 2023

Eurasian Journal of Applied Biotechnology

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In the pediatric population, coronavirus infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is more commonly observed in asymptomatic and moderately symptomatic cases. However, when COVID-19 coexists with other infections, it can result in a more severe disease progression. Various subtypes of the SARS-CoV-2 virus are associated with different clinical presentations, with certain subtypes exhibiting a predominance of specific symptoms or manifestations. Clinical manifestations of COVID-19 in children, both during the acute phase of the disease and in the post-COVID-19 period, are not fully understood and different compared to adults. This article presents four clinical cases in which PCR-confirmed COVID-19 was observed in combination with infections caused by viruses such as Ebstein-Barr, varicella, and rotavirus. The severity of the disease in these cases was attributed to symptoms related to intoxication, as well as skin and intestinal syndromes. To understand important genomic signatures of SARS-CoV-2 virus circulating in the area, the genome-wide sequencing was performed for the SARS-CoV-2 samples isolated from nasopharyngeal swabs collected from four patients. Based on the genotyping results, all four samples were found belonging to the SARS-CoV-2 virus Omicron lineage. Three months after the initial testing, follow-up evaluations of the children indicated a higher likelihood of complete recovery. However, some underlying disease manifestations, including anemia and atopic dermatitis, persisted despite the resolution of COVID-19 symptoms.

show abstract

Мультисистемный Воспалительный Синдром, Ассоциированный С Covid-19 У Детей, Как Исход Легких Форм Заболевания

Cited by 2 publications

References 21 publications

Current Aspects of the Clinical Course of Covid-19 in Children. Clinical Cases

Current Aspects of the Clinical Course of Covid-19 in Children. Clinical Cases

Co-Infection With Covid-19 and Genetic Diversity of Sars-Cov-2 in Children

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