The influence of climacteric osteoporosis on the process of osseointegration of dental implants is considered. Particular attention is paid to the relationship between menopause, osteoporosis and the success of osseointegration. In this regard, strategies for optimizing osseointegration are discussed, including the use of drugs to increase bone density and leveling of menopause symptoms in the period of preparation for implantation, the use of agents to improve the quality of osseointegration during and after implantation. Prospects and directions for further research in this area are determined.