РЕГУЛЯЦИЯ ФОРМИРОВАНИЯ БИОПЛЕНОК ESCHERICHIA COLI (ОБЗОР), "Прикладная Биохимия И Микробиология"

Маркова, Ю. А.; Анганова, Е. В.; Турская, А. Л.; Быбин, В. А.; Савилов, Е. Д.

doi:10.7868/s0555109918010014

Прикладная биохимия и микробиология

2018

DOI: 10.7868/s0555109918010014

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РЕГУЛЯЦИЯ ФОРМИРОВАНИЯ БИОПЛЕНОК ESCHERICHIA COLI (ОБЗОР), "Прикладная Биохимия И Микробиология"

Ю. А. Маркова¹,

Е. В. Анганова²,

А. Л. Турская³

et al.

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Phenotypic Mechanisms of Biofilm Resistance to Antibiotics

Savilov,

Markova,

Belkova

2024

Annals RAMS

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Considering that the current global problems are a trend towards increasing resistance of microorganisms to antibiotics and issues related to biofilm infections, the purpose of this review was to analyze modern data on the population level of biofilm resistance, which explains their increased resistance to antibiotics. One of the main introductory postulates is that the bacteria in a biofilm have not only genetic, but also phenotypic mechanisms of resistance to antibiotics, which is due to the population level of biofilm organization. This study revealed the main causes of phenotypic resistance of biofilms: quorum sensing, matrix composition, heterogeneity of microbial populations due to the biofilm architecture, and the mechanisms of persister cell formation. In conclusion, the relevance of considering the phenomenon of collective resistance of bacterial cells to antibacterial drugs in biofilm consortia in relation to infectious agents is summarized for a detailed understanding of the issue under consideration and the formation of appropriate programs in the clinical and preventive fields of medical science.

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Phenotypic Mechanisms of Biofilm Resistance to Antibiotics

Savilov,

Markova,

Belkova

2024

Annals RAMS

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show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

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РЕГУЛЯЦИЯ ФОРМИРОВАНИЯ БИОПЛЕНОК ESCHERICHIA COLI (ОБЗОР), "Прикладная Биохимия И Микробиология"

Cited by 1 publication

References 0 publications

Phenotypic Mechanisms of Biofilm Resistance to Antibiotics

Phenotypic Mechanisms of Biofilm Resistance to Antibiotics

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