Современные Тенденции Применения Локальных Аппликационных Кровоостанавливающих Средств

Александрович, Липатов Вячеслав; Павлович, Ершов Михаил; Александрович, Сотников Константин; Александрович, Ушанов Александр; Владимировна, Новикова Наталья; Евгеньевна, Константинова Юлия

doi:10.21626/innova/2016.2/07

Cited by 5 publications

(5 citation statements)

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“…Гемостатическая активность порошка складывается из совокупности физико-химических свойств (степени дисперсии гранул, адсорбционной, поглотительной способности и пр. ), которые определяются его структурными свойствами [3][4][5].…”

Section: Introductionunclassified

Studying the Efficacy of Local Hemostatic Agents In Vivo

Lipatov,

Tsilenko,

Denisov

et al. 2023

Innovacionnaâ medicina Kubani

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Introduction: In modern clinical practice, there is no common and effective hemostatic agent for solid organs of the abdomen. Local agents such as hemostatic sponges, membranes, powders seem promising. The main advantages of hemostatic powders include relatively high efficacy, portability, versatility, as well as simplicity and low cost of manufacturing.Objective: To study the hemostatic efficacy of hemostatic powders’ samples based on the sodium salt of carboxymethylcellulose (Na-CMC) in an acute in vivo experiment.Materials and methods: The study was based at Kursk State Medical University. Fifty male Wistar rats (weighing 220-239 g) were selected as test animals. They were evenly divided into 5 groups: ARISTA AH, Cutanplast Powder, and Na-CMC hemostatic powders with 3 different dynamic viscosities: low (50-200 cP), medium (400-800 cP) and high (1500-3000 cP). Under general inhalation anesthesia, median laparotomy was performed in Wistar rats, the middle lobe of the liver was removed into the wound, and then marginal tangential resection was performed. We applied hemostatic powders of each group to the resulting wound, and then estimated the bleeding time and the volume of blood loss. We used the Mann-Whitney test (P ≤ .05) to assess the statistical significance of differences between the study groups.Results: We recorded the minimum bleeding time and the smallest volume of blood loss for the samples based on the Na-CMC and found no statistically significant differences between the viscosities groups.Conclusions: With Na-CMC hemostatic powder the bleeding time and the volume of blood loss were reduced by 3.6 and 2.2 times, respectively, comparing to the control group. These results were considered statistically significant (P ≤ .05).

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Section: Introductionunclassified

Studying the Efficacy of Local Hemostatic Agents In Vivo

Lipatov,

Tsilenko,

Denisov

et al. 2023

Innovacionnaâ medicina Kubani

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“…Bleeding is a potentially life-threatening complication after thyroid surgery. The prevalence of bleeding is 0.36-4.3% [1,5]. The frequency of postoperative neck hematoma during thyroid surgery requiring reoperation ranges from 0 to 9.1% and is the most common reason for returning to the operating room.…”

Section: Introductionmentioning

confidence: 99%

The Significance of Local Intraoperative Hemostasis and Laser Influence in the Prevention and Treatment of Complications During Thyroid Surgery

Kasymov A.L,

Mansurov Sh.Sh,

Musashaikhov X.T

et al. 2023

Texa. Jour. of Medi. Scie.

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The article presents the results of clinical studies on the development of a method for local intraoperative hemostasis and improvement of reparative processes during operations on the thyroid gland. For clinical evaluation of the effectiveness of the proposed method, two study groups were formed for 237 patients with mixed, nodular and diffuse toxic goiter. The main group consisted of 98 patients, and the comparison group - 139. In the main group of operated patients, hemostasis was carried out according to the method developed by us, and in the comparison group, by traditional methods. Surgery included thyroidectomy, hemithyroidectomy, and subtotal thyroidectomy. In the main group of patients, for the purpose of hemostasis, Hemoben powder crystals with a size of 25-50 microns were used at the rate of 200 mg per area of 8-9 cm2, which was applied over the wound with a thin layer until a thin translucent film was formed, followed by irradiation of the wound with low-energy laser radiation (Sogdiana apparatus) with a wavelength of 0.89 microns, a frequency of 500 Hz for 2 minutes at a distance of 5 cm from the wound; then, for 5-7 days, percutaneous irradiation sessions with the same laser at a frequency of 80 Hz were performed daily in the projection of the surgical wound. The study showed that the use of the domestic hemostatic agent Hemoben provides complete hemostasis, and the addition of the technique by treating the surgical field with low-intensity laser radiation enhances the reparative properties of the drug. The proposed method for local hemostasis and improvement of reparative processes during thyroid surgery is characterized by a quick, effective and stable stop of bleeding, prevents the development of lymphohemorrhagic complications, and also reduces the frequency of early postoperative complications due to intra- and postoperative laser exposure.

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“…Bir vaqtda amalga oshiriladigan operatsiyalar bemorlarni takror shifoxonaga yotkazish, anesteziologik xavf va u bilan bog'liq psixoemotsional travmalardan xalos etadi, bemorlarning vaqtinchalik mehnatga layoqatsizlik holati ancha qisqaradi, bemorlar uchun operatsiyadan keyingi davrning noxush omillari bartaraf etiladi, davolash uchun sarfl anadigan umumiy iqtisodiy harajatlar kamayadi [1,7,15]. Bundan tashqari, xirurgik davolashni bir necha bosqichda amalga oshirilishi hamma vaqt ham mumkin emas va bu qator ob'ektiv ijtimoiyiqtisodiy sabablar, bemorning qayta operatsiyaga rozi bo'lmasligi yoki kelmasligi, zarur jihozlarning etishmasligi va boshqalar bilan bog'liq bo'lishi mumkin [10,14].asoratlarni keltirib chiqarmaydi va 89,9% holatda xirurgik korreksiyaning ishonchli uzoq muddatli ijobiy natijasiga erishish imkonini beradi [8,10].…”

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Burun bo'shlig'i turli patologiyalarda simultan jarroxlik aralashuvlaridan keyingi klinik–funksional natijalar

Xasanov

Raximov

Djurayev

2023

EJOHNS

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Hozirgi kunda otorinolaringologiya soxasida burun bo'shlig`larida turli xil jarroxlik amaliyotlari o'tkazilib keladi. Burun bo'shlig`larining zamonaviy jarroxlik amaliyotlarida simultan operatsiyalar ("simultaneous" angl. – bir vaqtda) – bu bir yoki bir necha anatomik sohalardagi turli a’zolarning ikki yoki undan ortiq kasalliklarini bir vaqtning o‘zida xirurgik korreksiyalashga yo‘naltirilgan murakkab operativ amaliyotlar keng o'tkazilib kelinmoqda.Turli xil zamonaviy jarroxlik amaliyotlariga qaramasdan kasalliklar qaytalanishi, kon ketishlar, tuzalish bosqichining uzayishi va asoratlanish xolatlari nisbatan ko`p uchramoqda.Burun shilliq qavatining xolatini baholash turli xil klinik ,endoskopik natijalar asosida baholandi. Adabiyotlarda mualliflar tomonidan zamonaviy qo`shma jarroxlik amaliyotlarida eng ko’p uchraydigan holatlardan biri burun shilliq qavatining butunligini buzilishidir.

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Современные Тенденции Применения Локальных Аппликационных Кровоостанавливающих Средств

Cited by 5 publications

References 0 publications

Studying the Efficacy of Local Hemostatic Agents In Vivo

Studying the Efficacy of Local Hemostatic Agents In Vivo

The Significance of Local Intraoperative Hemostasis and Laser Influence in the Prevention and Treatment of Complications During Thyroid Surgery

Burun bo'shlig'i turli patologiyalarda simultan jarroxlik aralashuvlaridan keyingi klinik–funksional natijalar

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