Сустав. Хрящ. Коллаген

Yaremenko, O.B.; Anokhina, H.A.; Burianov, О.A.

doi:10.22141/1608-1706.4.21.2020.212531

Cited by 3 publications

(3 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Another important potential "target" of the negative impact of cadmium compounds on the musculoskeletal system is articular cartilage, which consists of chondrocytes, water, type II collagen and proteoglycans. The structure and composition of articular cartilage is influenced by age, gender, genes, and the environment, and collagen and proteoglycans provide the basis for the cartilage matrix to maintain a stable metabolism and normal physiological and biochemical functions [32,33]. The main proteoglycan in cartilage is the high molecular weight protein ACAN, which interacts with hyaluronic acid to form high molecular weight polymers, resulting in high elasticity [34].…”

Section: Main Partmentioning

confidence: 99%

“…Ще однією з важливих потенційних «мішеней» негативного впливу сполук кадмію на опорно-рухову систему організму є суглобові хрящі, до складу яких входять хондроцити, вода, колаген ІІ типу та протеоглікани. На структуру та склад суглобового хряща впливають вік, стать, гени та зовнішнє середовище, а колаген та протеоглікани забезпечують основу, яка дозволяє матриксу хряща підтримувати стабільний метаболізм та нормальні фізіологічні та біохімічні функції [32,33]. Основний протеоглікан у хрящі -це високомолекулярний білок ACAN, який взаємодіє з гіалуроновою кислотою, утворюючи високомолекулярні полімери, обумовлюючи високу еластичність [34].…”

Section: огляди літератури / Literature Reviewsunclassified

See 1 more Smart Citation

Influence of Heavy Metals on Morpho-Functional State of Bone Tissue

Shatorna

2024

VPBM

View full text Add to dashboard Cite

Вісник проблем біології і медицини -2024 -Вип. 1 (172) / Bulletin of problems in biology and medicine -2024 -Issue 1 (172) 75ОГЛЯДИ ЛІТЕРАТУРИ / LITERATURE REVIEWS tissue diseases, dysmenorrhea and abnormal uterine bleeding are the most common menstrual disorders, caused by immune dysregulation, autoimmune processes, and inflammation. The modern approach to the treatment of such patients consists in the development of an individual treatment plan, taking into account concomitant diseases, current laboratory findings, pathological features of the onset of the disease and the course of menstrual cycle disorders. Treatment consists of prescribing hormonal (synthetic and natural estrogens, gonadotropin-releasing hormones, progesterone and gonadotropin-releasing hormone analogues) and non-hormonal agents (nonsteroidal anti-inflammatory drugs, tranexamic acid), as well as non-drug treatment (lifestyle modification, physical activity, rational nutrition). To date, there is no unified terminology and generally accepted criteria for diagnosing and assessing the severity of UCTD. Diagnostic methods and criteria for UCTD are not standardized compared to other connective tissue diseases. Management of patients with connective tissue diseases and menstrual dysfunction is a complex issue, the answer to which is based on the assessment of gynecological problems (menstruation, fertility, sexuality) and a multidisciplinary approach involving specialists from other branches.

show abstract

Section: Main Partmentioning

confidence: 99%

Section: огляди літератури / Literature Reviewsunclassified

Influence of Heavy Metals on Morpho-Functional State of Bone Tissue

Shatorna

2024

VPBM

View full text Add to dashboard Cite

show abstract

“…MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions, or products referred to in the content. maintaining of the musculoskeletal system performance is possible with the use of collagen derivatives in a daily dose of 10 g for 1-6 months [11].…”

Section: Introductionmentioning

confidence: 99%

An Isotonic Drink containing Pacific cod (<em>Gadus macrocephalus</em>) Processing Waste Collagen Hydrolysate for Prevention of Bone and Cartilage Disorders

Zarubin¹,

Kharenko²,

Bredikhina³

et al. 2022

Preprint

View full text Add to dashboard Cite

Malnutrition is one of major factors of bone and cartilage disorders. Pacific cod (Gadus macrocephalus) processing waste is a cheap and highly promising source of bioactive substances, including collagen-derived peptides and amino acids, for bone and cartilage structure stabilization. Addition of these substances to a functional drink is one of the ways to achieve their fast intestinal absorption. Collagen hydrolysate was obtained via enzymatic hydrolysis, ultrafiltration, freeze-drying, and grinding to powder. The lyophilized hydrolysate was a light gray powder with high protein content (>90%), including collagen (about 85% of total protein) and a complete set of essential and non-essential amino acids. The hydrolysate was applicable as a protein food supply or a structure-forming food component due to presence of collagen fiber fragments. An isotonic fitness drink (osmolality 298.1 ± 2.1 mOsm/L) containing the hydrolysate and vitamin C as a cofactor in collagen biosynthesis was prepared. Addition of the hydrolysate did not adversely affect its organoleptic parameters. Production of such functional foods and drinks is one of the beneficial ways of fish processing waste utilization.

show abstract

An Isotonic Drink Containing Pacific Cod (Gadus macrocephalus) Processing Waste Collagen Hydrolysate for Bone and Cartilage Health

Zarubin,

Kharenko,

Bredikhina

et al. 2024

Marine Drugs

View full text Add to dashboard Cite

Malnutrition is one of the major factors of bone and cartilage disorders. Pacific cod (Gadus macrocephalus) processing waste is a cheap and highly promising source of bioactive substances, including collagen-derived peptides and amino acids, for bone and cartilage structure stabilization. The addition of these substances to a functional drink is one of the ways to achieve their fast intestinal absorption. Collagen hydrolysate was obtained via enzymatic hydrolysis, ultrafiltration, freeze-drying, and grinding to powder. The lyophilized hydrolysate was a light gray powder with high protein content (>90%), including collagen (about 85% of total protein) and a complete set of essential and non-essential amino acids. The hydrolysate had no observed adverse effect on human mesenchymal stem cell morphology, viability, or proliferation. The hydrolysate was applicable as a protein food supply or a structure-forming food component due to the presence of collagen fiber fragments. An isotonic fitness drink (osmolality 298.1 ± 2.1 mOsm/L) containing hydrolysate and vitamin C as a cofactor in collagen biosynthesis was prepared. The addition of the hydrolysate did not adversely affect its organoleptic parameters. The production of such functional foods and drinks is one of the beneficial ways of fish processing waste utilization.

show abstract

Сустав. Хрящ. Коллаген

Cited by 3 publications

References 1 publication

Influence of Heavy Metals on Morpho-Functional State of Bone Tissue

Influence of Heavy Metals on Morpho-Functional State of Bone Tissue

An Isotonic Drink containing Pacific cod (<em>Gadus macrocephalus</em>) Processing Waste Collagen Hydrolysate for Prevention of Bone and Cartilage Disorders

An Isotonic Drink Containing Pacific Cod (Gadus macrocephalus) Processing Waste Collagen Hydrolysate for Bone and Cartilage Health

Contact Info

Product

Resources

About