For the first time, a comparative analysis of spatial-temporal changes in macrophytobenthos based on a landscape approach was performed in the Laspi Bay for the period from 1983 to 2008. Landscape maps of the Laspi Bay was created, the distribution of the bottom natural complexes with the key Black Sea phytocoenoses was shown. It was found that the plant components of the bottom natural complexes in the Laspi Bay had undergone significant restructuring and degradation during 25 years due to the impact of natural factors and anthropogenic activities in the coastal zone.