Ischemic stroke is a major medical and social problem, as it is characterized by high rates of morbidity, disability and mortality. Non-invasive diagnostic methods, such as magnetic resonance and computed tomography, make it possible to visualize this pathology and, based on the results obtained, formulate a diagnosis in order to prescribe appropriate therapy for effective treatment and improve the prognosis of the disease. In recent years, the concept of prehospital diagnosis of ischemic stroke has been introduced, including mobile ultrasound machines for ultrasound examination of cerebral perfusion, as well as mobile stroke units (MSU). It was found that treatment in the MSU, including prehospital imaging, resulted in significantly better clinical outcomes, both because of early initiation of systemic thrombolysis in the golden hour and because of improved triage of patients for subsequent endovascular thrombectomy. Further financial and economic evaluation of mobile stroke units is needed, including the analysis of the cost-effectiveness of the investment project and the possibilities of introducing this innovative approach to stroke diagnosis and treatment in Russia.