Тіазиди Або Тіазидоподібні Діуретики В Лікуванні Артеріальної Гіпертензії?

Radchenko, G.

doi:10.22141/2224-1485.6.56.2017.120323

2022

DOI: 10.22141/2224-1485.6.56.2017.120323

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Тіазиди Або Тіазидоподібні Діуретики В Лікуванні Артеріальної Гіпертензії?

G. Radchenko¹

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Thiazide and thiazide-like diuretics: how to make the right choice?

et al. 2022

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Most patients with arterial hypertension (AH) require a combination treatment to achieve the goal blood pressure. According to Russian and international clinical guidelines on the treatment of AH patients, various antihypertensive drugs may be combined; however, not all combinations have similar profiles of safety and clinical efficacy. In this respect, special attention is given to combinations of renin-angiotensin-aldosterone system inhibitors and thiazide (hydrochlorothiazide) or thiazide-like (chlortalidone, indapamide) diuretics. Diuretics also differ in their mechanisms of action, presence of pleiotropic effects and organ-protective properties, effects on the prognosis, and in the evidence base. This review discusses the place of thiazide and thiazide-like diuretics in the treatment of patients with AH and provides an evaluation of major differences in pharmacological and clinical effects of drugs of the diuretic class.

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Thiazide and thiazide-like diuretics: how to make the right choice?

et al. 2022

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Тіазиди Або Тіазидоподібні Діуретики В Лікуванні Артеріальної Гіпертензії?

Cited by 1 publication

References 47 publications

Thiazide and thiazide-like diuretics: how to make the right choice?

Thiazide and thiazide-like diuretics: how to make the right choice?

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