دراسات بیولوجیة وتغذویة علاجیة علی الفئران السمینة باستخدام أعشاب الراوند والقتاده

Abstract

This investigation aimed to evaluate the effect of Rhubarb, Astragalus and Mixture of both on male obese rats. Thirty (30) adult male Sprague Dawley rats were divided into five groups. Group (1): Normal rats fed on basal diet as control negative (C-), Group (2): Control positive (C+) (untreated group). Group (3): Obese rats fed on basal diet and rhubarb (5%).Group ( 4): Obese rats fed on basal diet and astragalus (5%). Group ( 5): Obese rats fed on basal diet and mixture of both (5%). At the end of experiment, after 28 days of feeding, all serum samples were analyzed for biochemical parameters. Obese rats caused a significant increases in the level of PFP%, leptin hormone and organs weight (liver, heart, spleen, lungs and kidneys), while significant decreases recorded in SOD, GPX and CAT. Obese rats treated with various diets, showed the improvement in all previous parameters.