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Significance Traditional highresolution microscopy techniques are limited in imaging within confined and narrow spaces, such as the cavities of animals or the inner chambers of precision instruments, due to their bulky and complex systems. Microscopic endoscopy technology allows for highresolution observations within cavities by inserting miniature probes. Common types of endoscopes include rigid endoscopes composed of purely optical lenses and electronic endoscopes using image sensors, with diameters typically ranging from millimeters to centimeters. To achieve imaging systems with even smaller diameters, researchers have begun to explore the use of fiber bundles or single fibers for miniature endoscopic imaging. However, these systems typically require gradient refractive index lenses or scanning devices, resulting in diameters much larger than the imaging field and encountering issues such as edge aberrations and honeycomb noise. In recent years, ultrathin lensless multimode fiber (MMF) endoscopes have emerged as a new research hotspot, achieving numerous breakthroughs in imaging modes such as real sample imaging and image transmission.MMFs, as a type of multimode linear system, have historically been regarded as unpredictable due to their rich spatiotemporal modes (phase, amplitude, polarization, wavelength, and pulse delay) and the sensitive and complex mode coupling characteristics. With recent advancements in optical wavefront shaping and optical field measurement technologies, significant strides have been achieved in controlling optical fields within MMFs. This progress positions 1026017 -15 特邀综述 第 44 卷 第 10 期/2024 年 5 月/光学学报 them as promising candidates for a new generation of minimally invasive superresolution endoscopic imaging tools. In comparison to traditional endoscopes, MMF endoscopy technology presents several notable advantages. Firstly, it fully exploits the spatial multiplexing capability of fibers, resulting in ultrahigh mode density. Moreover, its spatial bandwidth product exceeds that of fiber bundle endoscopes by an order of magnitude under identical probe diameters. Secondly, no additional lens system is required at the fiber probe end, reducing probe size and encapsulation requirements substantially.Thirdly, leveraging MMFs as the transmission medium enables the creation of complex threedimensional light field distributions at the fiber exit end through encoded wavefront modulation techniques and mode calculations. This facilitates threedimensional scanning imaging of samples, yielding more comprehensive and detailed sample information than traditional methods. Furthermore, MMFs fabricated from inert and biocompatible hydrogel materials can be directly integrated into disposable medical endoscopic systems. Overall, MMFbased endoscopic detection systems have made significant advancements and are poised to complement traditional endoscopic techniques in achieving highprecision detection in confined spaces. Nonetheless, the feasibility and performance enhancement of this technology in medi...
Significance Traditional highresolution microscopy techniques are limited in imaging within confined and narrow spaces, such as the cavities of animals or the inner chambers of precision instruments, due to their bulky and complex systems. Microscopic endoscopy technology allows for highresolution observations within cavities by inserting miniature probes. Common types of endoscopes include rigid endoscopes composed of purely optical lenses and electronic endoscopes using image sensors, with diameters typically ranging from millimeters to centimeters. To achieve imaging systems with even smaller diameters, researchers have begun to explore the use of fiber bundles or single fibers for miniature endoscopic imaging. However, these systems typically require gradient refractive index lenses or scanning devices, resulting in diameters much larger than the imaging field and encountering issues such as edge aberrations and honeycomb noise. In recent years, ultrathin lensless multimode fiber (MMF) endoscopes have emerged as a new research hotspot, achieving numerous breakthroughs in imaging modes such as real sample imaging and image transmission.MMFs, as a type of multimode linear system, have historically been regarded as unpredictable due to their rich spatiotemporal modes (phase, amplitude, polarization, wavelength, and pulse delay) and the sensitive and complex mode coupling characteristics. With recent advancements in optical wavefront shaping and optical field measurement technologies, significant strides have been achieved in controlling optical fields within MMFs. This progress positions 1026017 -15 特邀综述 第 44 卷 第 10 期/2024 年 5 月/光学学报 them as promising candidates for a new generation of minimally invasive superresolution endoscopic imaging tools. In comparison to traditional endoscopes, MMF endoscopy technology presents several notable advantages. Firstly, it fully exploits the spatial multiplexing capability of fibers, resulting in ultrahigh mode density. Moreover, its spatial bandwidth product exceeds that of fiber bundle endoscopes by an order of magnitude under identical probe diameters. Secondly, no additional lens system is required at the fiber probe end, reducing probe size and encapsulation requirements substantially.Thirdly, leveraging MMFs as the transmission medium enables the creation of complex threedimensional light field distributions at the fiber exit end through encoded wavefront modulation techniques and mode calculations. This facilitates threedimensional scanning imaging of samples, yielding more comprehensive and detailed sample information than traditional methods. Furthermore, MMFs fabricated from inert and biocompatible hydrogel materials can be directly integrated into disposable medical endoscopic systems. Overall, MMFbased endoscopic detection systems have made significant advancements and are poised to complement traditional endoscopic techniques in achieving highprecision detection in confined spaces. Nonetheless, the feasibility and performance enhancement of this technology in medi...
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