국내 다기관 전향적 코호트 연구를 통한 우리나라 뇌졸중 환자의 발병 5년 생존율과 재발률

Abstract

The purpose of this study was to report five-year survival and recurrence rate after first-time stroke using the data obtained by multicenter prospective cohort study in Korea. This study was an interim analysis of the Korean Stroke Cohort for Functioning and Rehabilitation (KOSCO). Data of 10,636 first-time stroke patients (8,210 ischemic and 2,426 hemorrhagic) who were admitted to the 9 district hospitals of Korea were analyzed. In order to compensate the missing values due to the follow-up failure, KOSCO data were linked with the National Health Insurance Service data until 2020. Mortality and recurrence rate up to five years were estimated by Kaplan-Meier estimation and the Cox regression analysis. The oneyear cumulative mortality rate was 11.8%, the three-year 18.9%, and the five-year 25.2%. Ischemic stroke, male, older age, combined diseases, hypertension, in-hospital pneumonia, lack of intensive rehabilitation, moderate to severe initial stroke severity (National Institutes of Health Stroke Scale >15), low initial motor function (Fugl-Meyer Assessment <85), and low ambulatory functions (Functional Ambulatory Category 0-3) showed higher hazard ratio for mortality (p<0.05). The one-year cummulative recurrence rate was 8.9%, the three-year 12.7%, and the five-year 15.5%. According to Cox regression analysis, stroke type (ischemic) and initial stroke severity were significant factors for stroke recurrence (p<0.05). Of the factors affecting 5-year mortality after first-time stroke, two modifiable factors were defined as pneumonia and intensive rehabilitation during the first admission period.

Effects of Robot-Assisted, Gait-Training-Combined Virtual Reality Training on the Balance and Gait Ability of Chronic Stroke Patients

“…뇌졸중은 뇌의 혈류가 차단되어 발생하고, 뇌세포는 산소가 공급 중단되면 죽기 시작하여, 세포의 죽음은 근육 조절 등의 뇌 영역에 통제 능력을 상실하게 되는 것을 말한다 [1]. 현재 뇌졸중 환자의 5년 생존률은 상대 적으로 높은것으로 나타나고 있으나, 장기적인 관리가 필요하다 [2]. 또한 뇌졸중은 이러한 손상으로 인해 신 경학적 결손을 보이게 되며, 신체의 운동능력, 감각, 지각, 언어 등의 장애를 유발시킨다 [3].…”

Factors Influencing the Quality of Life of Family Caregivers of Stroke Patients: A Cross-Sectional Survey

“…A stroke is a neurological condition characterized by damage to a specific area of the brain because of the blockage or rupture of a blood vessel supplying blood to the brain [1]. It has been identified as a significant contributor to mortality and disability in South Korea.…”

“…Notably, it accounts for the highest rates of single-disease deaths. A multicenter prospective cohort study conducted in Korea found that the 5-year survival rate after stroke is 74.8%, but 23.8~38.6% of these stroke survivors experience residual disability related to motor function, cognitive function, language, and mobility [1]. These disabilities can cause financial burdens and affect the daily functioning and quality of life of both patients and their families [2].…”