The present article gives an analytical overview of the current state of processing problems and visualization of magnetic resonance imaging (MRI). It is presented the expediency of combining of instrumental means, presented in various open-source programs and scientific publications in recent years, into a single program-tool complex solving in full problems of pre-processing and filtering data, directed precision thematic segmentation and analysis of images, forming the feature space, recognition of the situation, 3D modeling, and visualization. The complex is designed for expert decision support of doctors-researchers in the process of carrying out scientific experiments. Support is based on the application of new methods of brain area texture analysis, effective metrics, and advanced means of cognitive computer graphics. An important feature of the complex must be the interactive operating mode of the doctor-researcher with MRI data, which can be provided by applying high-performance computing with software support of hardware accelerators.

During the period from 1988 to 2000 the compensation lower limb shortening was performed in 285 patients, aged 2.5-18 years, at CITO Pediatric Orthopaedic Clinik. In 5 patients with severe extremity malformation and severe vascular pathology surgical interventions aimed at facilitation of subsequent prosthesis and orthesis. The other patients were subjected to surgical correction using rod distraction device of original design. Complex rehabilitation treatment including functional biocontrol was started in the early postoperative period. The condition of distraction regenerate was evaluated by X-ray, CT and Doppler Laser Flowmetry data. In 63 patients with congenital lower extremity pathology in whom insufficient regeneration was observed the implants containing fetal bone tissue were inserted into the regenerate zone resulting in marked osteogenic effect. Suggested treatment allowed to improve the outcomes and shorten the terms of treatment.

The evaluation of the CT efficacy for the elaboration and realization of low invasive diagnosis and treatment in bone pathology was performed. Sixty two patients, aged from 6 to 80, were examined. The method of stereotaxic determination of pathologic locus localization with CT controlled manipulation (target biopsy, anchor navigation in disorder focus, injection of contrast matter and introduction of plastic materials into the focus) was used. The efficacy of those method made up 89.6% for target biopsy corresponding to the high degree accuracy of pathological process identification and 100%) for the preoperative marking. New elaborated method is accurate and safe for the patients.

It is for the first time that the clinical picture, diagnosis and outcomes of surgical treatment of bone chondroblastoma in children (85 patients, aged 816) are described in native literature. Pathological focus was localized in the epiphysis and metaepiphysis of long bone predominantly. Clinical manifestations were pain syndrome, restriction of movement and development of contracture in the adjacent joint. Typical radiological signs included excentrically located osteolytic locus of destruction with speckled inclusions and clear contour. The locus was separated by sclerosis line and periostal stratums were present in the distance from the locus. CT, MRT and angiographic examination enabled to determine the destructive locus at early stages of its development and to differentiate with other tumors, inflammatory diseases and dystrophic processes. In all cases diagnosis was verified morphologically. All patients underwent surgery. In the majority of cases periarticular subchondral resection with cavity electrocoagulation and alloplasty of the defect was performed. In case of articular cartilage destruction intracapsular marginal or segmental resection followed by allo- or autoplasty of the defect was carried out. Recurrences were observed in 8,2%) of cases. In 8 patients shortening or deformity of limb developed as a result of growth zone damaged caused by pathological process and surgical intervention. Those problems were eliminated by additional surgery.

Retrospective analysis of radiographic semiotics in tumors and tumor-like diseases of spine was performed in 179 children, aged 3-16. Fourteen nosologic forms were revealed, diagnosis was verified morphologically. Eleven patients had malignant tumors (osteogenic sarcoma, Ewings sarcoma, malignant osteoblastoma, chondrosarcoma, malignant neuroblastoma); 67 patients had benign tumors (osteoid-osteoma, osteoblastoma, hemangioma, osteoblastoclastoma, osteochondroma, neurogenic tumors, chondroma); tumor-like diseases were revealed in 101 patients (aneurismal bone cyst, eosinophilic granuloma). The peculiarities of radiographic semiotics were described for every nosologic form, differential diagnostic criteria for the most common tumors and tumor-like diseases have been presented.