Objective: Detection of trend, its analytical description and forecasting of time series for short-term and long-term periods for modeling the development of epidemiological processes in syphilitic infection. Materials and methods: MATLAB application package was used to develop an automatic analysis system for time series monitoring of the development of epidemiological processes for their forecasting. The Financial Toolbox library was used to analyze time series. Results: Mathematical models of trends were obtained for the existing time series, and the effectiveness of using an exponential trend in the declining phase of the syphilis epidemic was shown. The coefficient of determination R2 = 0.9956 indicates that the model explains 99.56% of the variance (the approximation error is 0.44%). However, such high accuracy of approximation (and accordingly, forecast accuracy) is true only if a new outbreak of the epidemic is unlikely during the forecast period. If the real data start deviating from the forecast (increase to at least 10,000 cases per year), a new wave of the infection process can be detected.

The aim. Study of the state of the microcirculatory bed in patients with late syphilis with the aim of timely correction of vascular complications of the disease. The results. A clinical case from the practice of dermatovenerologist doctors is given. Conclusions. The key goal of preventing a severe course of syphilis should be to stabilize the microcirculatory channel. For the timely detection of vascular disorders, it is sufficient to determine the perfusion index by pulse oximetry.

патологии позвоночника и суставов им. проф. М. И. Ситенка НАМН Украины» Резюме С учетом роста распространенности поздних форм сифилиса среди населения, с целью предотвращения диагностических ошибок, связаных с редкостью выявления сифилиса у больных неврологических и соматических стационаров, приведен клинический случай из практической деятельности врачей-дерматовенерологов.

The objective. Prevention of diagnostic errors associated with the rare detection of syphilis in patients in neurological hospitals. Results. A clinical case from the practice of dermatovenereologists is given. Conclusions. For timely detection of neurosyphilis it is necessary to conduct a cerebrospinal fluid examination of all patients in the neurological hospital who have a positive result of non-treponemal and treponemal tests in the serum.