Permalloy-based thin film structures are excellent materials for sensor applications. Temperature dependencies of the magnetic properties and giant magneto-impedance (GMI) were studied for Fe19Ni81-based multilayered structures obtained by the ion-plasma sputtering technique. Selected temperature interval of 25 °C to 50 °C corresponds to the temperature range of functionality of many devices, including magnetic biosensors. A (Cu/FeNi)5/Cu/(Cu/FeNi)5 multilayered structure with well-defined traverse magnetic anisotropy showed an increase in the GMI ratio for the total impedance and its real part with temperature increased. The maximum of the GMI of the total impedance ratio ΔZ/Z = 56% was observed at a frequency of 80 MHz, with a sensitivity of 18%/Oe, and the maximum GMI of the real part ΔR/R = 170% at a frequency of 10 MHz, with a sensitivity of 46%/Oe. As the magnetization and direct current electrical resistance vary very little with the temperature, the most probable mechanism of the unexpected increase of the GMI sensitivity is the stress relaxation mechanism associated with magnetoelastic anisotropy.
The temperature dependencies of magnetoimpedance (MI) and stress impedance (SI) were analyzed both in the as-quenched soft magnetic Co68.5Fe4Si15B12.5 ribbons and after their heat treatment at 425 K for 8 h. It was found that MI shows weak changes under the influence of mechanical stresses in the temperature range of 295–325 K and SI does not exceed 10%. At higher temperatures, the MI changes significantly under the influence of mechanical stresses, and SI variations reach 30%. Changes in the magnetoelastic properties for the different temperatures were taken into consideration for the discussion of the observed MI and SI responses. The solutions for the problem of thermal stability of the magnetic sensors working on the principles of MI or SI were discussed taking into account the joint contributions of the temperature and the applied mechanical stresses.
Polymorphism of glutathione S transferase (GSTA1, GSTM1, GSTM3, GSTP1, and GSTT1) and DNA repair (ERCC1, ERCC2, and XRCC1) genes in samples of ovarian cancer patients and healthy women of the Russian ethnic group was studied. A trend in the allele frequency variation of ERCC2 gene single nucle otide polymorphism (rs13181, A > C) was revealed. The A allele frequency was higher in the sample of patients (60,6% versus 52,9%, P = 0.058).
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