The fourth industrial revolution opened new opportunities for the development of industrial processes, as it created the opportunity for companies to transform their conventional systems into cyber-physical systems to meet the increasingly dynamic and diversified customers’ demands. Although the primary goal of the development of these cyber-physical systems is to improve the efficiency of operations and increase the quality, but energy efficiency, environmental impact and sustainability also should be taken into consideration. Packaging is a special area of production and service, where due to the significant amount of logistics activity, the design and operation of sustainable processes with low environmental impact are emphasized. Within the frame of this article, the author provides an overview of the opportunities offered by Industry 4.0 technologies in the development of packaging processes of manufacturing and service companies and outlines the challenges to be faced in the implementation of these developments.