There is a rare association regarding inflammatory bowel diseases and cerebral venous thrombosis that can have a potential unfavourable outcome. Here we report a 29 year-old female patient with a severe form of pancolitis autoimmune disease and an incomplete superior sagittal sinus and bilateral transverse sinuses thrombosis with a clinical response of motor deficit in the right upper limb. With the implication of a multidisciplinary medical team and anticoagulant therapy the patient had a good neurologic outcome and we want to compare our case to the few other reported cases regarding associated pathologies, risk factors, treatment and outcome.