Background: Although anaphylaxis has been considered a priority public health issue in the world allergy community, epidemiological data on morbidity and mortality remain suboptimal. We performed the first multicenter epidemiological study in French emergency departments (EDs). The study covered 7 EDs over a period of 1 year. The objectives were to identify areas that are amenable to change and to support ongoing national and international efforts for better diagnosis, management, and prevention of anaphylaxis. Methods: Ours was a descriptive study based on data routinely reported to French institutional administrative databases from 7 French public health institutions in the Lorraine region between January and December 2015. Data were collected based on the anaphylaxisrelated codes of the International Classification of Diseases (ICD)-10, and cases were clinically validated as anaphylaxis. Results: Of the 202 079 admissions to the EDs, 4817 had anaphylaxis-related codes; of these, 323 were clinically validated as anaphylaxis. Although 45.8% were severe, adrenaline was prescribed in only 32.4% of cases. Of the 323 cases, 57.9% were subsequently referred for an allergy work-up or evaluation (after or during hospitalization), and 17.3% were prescribed autoinjectable epinephrine. Conclusion: Our results highlight an urgent need for improved public health initiatives with respect to recognition and treatment of anaphylaxis. We flag key problems that should be managed in the coming years through implementation of national and international actions.

In France, approximately 500 deaths per year are related to sudden infant death syndrome (SIDS). After a 75% reduction of SIDS-related deaths in the 1990s, thanks to large prevention campaigns directing parents to put their infants to sleep on their back, the number of SIDSrelated deaths remains stable. However we estimate that 100 to 200 deaths of infants per year in France could be preventable with a better education to the risk factors of SIDS.In this prospective and descriptive monocentric study, we aimed at evaluating the level of expecting women's knowledge about SIDS. Questionnaires were distributed during a midwife consult. A score about sleeping conditions, environment and protective factors was determined with coefficients attributed according to the relevance to SIDS.Out of 296 questionnaires distributed, 202 were completed and included in the analysis from March, 1 st to September, 21 th 2018. Score were distributed from 2 to 46/50. The average note was 28.6/50. Ways of getting information was principally from media and not health professionals. When the information was delivered by a caregiver, in particular by the paediatrician, we observed a better knowledge of these women. This study shows that it is important for health professionals to take the time to inform future mothers about risk factors of SIDS, especially the population the least informed such as young mothers and from lower socio-economic status, in order to decreases the number of infant's avoidable deaths.

We report a 10-year-old girl in whom Stevens-Johnson syndrome (SJS) (with acute gingivostomatitis and conjunctivitis) was associated with a pustular eruption clinically and histologically similar to Sneddon-Wilkinson subcorneal pustulosis. This is a very rare form of SJS, the true incidence of which is probably underestimated.

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