SummaryBackground. Owing to the spontaneous remission with no complication being the rule, pityriasis rosea (PR) has been termed Doctor's Delight. Only two patients have been reported to have Hodgkin lymphoma and atypical PR concomitantly. There exists no report on the association of PR and non-Hodgkin lymphoma. Case report. We present a 62-year-old male patient with fever and coryzal symptoms, followed by a herald patch at the right inferior quadrant of his anterior abdominal wall. One week later, generalised skin lesions erupted on his trunk and proximal aspects of his four limbs. We saw him 12 days after onset of the primary patch. Examination revealed clinical features entirely compatible with classical PR. Systemic examination revealed enlarged and firm inguinal lymph nodes bilaterally. Spontaneous rash resolution occurred two weeks later. As the inguinal lymph nodes were still enlarging over time, we referred him to a physician. Lymph node biopsy revealed non-Hodgkin lymphoma. Discussion. This is the first reported patient with non-Hodgkin lymphoma presenting as classical PR. PR in the elderlies, pregnant women, people with autoimmune diseases or tendencies, people after organ transplantation, and immunocompromised people might be at a higher risk of serious underlying diseases or severe complications, and are important exceptions for this Doctor's Delight.