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Medication Related errors are serious problems in health care and can be a source of significant mortality and morbidity. Hence, reporting is encouraged to know the incidence rates which helps in preventing them. The aim of this study was to identify and document Medication Related errors in hospitalized patients at a tertiary care center and to review the updated case sheets on prescribed medications, regularly. A prospective observational case analysis study was conducted between November 2013 and April 2014 at Gandhi Hospital, Secunderabad. A structured data collection form was prepared to document the case details for identification and documentation of drug(s) involved in Medication Related errors. Collected data was summarized categorically and analyzed to conclude the final outcome. Total of 71 of Medication Related errors were observed and documented. Patients with maximum Medication Related errors were male (70.42%). The study reported maximum errors of untreated indication (18) followed by a wrong dose (14). Route of administration showing maximum errors was in case of tablets 28 errors followed by 19 errors due to injections. Seven Point Severity scale (0-6) showed maximum Medication Related errors found to be of level 1 and level 2 (21 errors each). The study showed Medication Related Errors occur frequently in inpatient medical wards. Clinical pharmacist's interventions can effectively prevent these errors by identification and documentation at the early stage. This indicates the need for a continuous educational program to healthcare professionals on drug therapy problems which will help for better patient safety.