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Aim : The study was carried out to investigate the prevalence and antimicrobial susceptibility of clinical pathogens isolated from Bovine Mastitis in and around Coimbatore District, Tamilnadu, South India. Materials and Methods: A total of 250 milk samples were screened and 152 isolates of Staphylococci were obtained and their susceptibility to several antimicrobial agents by agar disc diffusion method. Results: Out of 152 isolates of Staphylococcus aureus resistance was detected in 63 (41.44%), 39 (25.65%), 21(13.81%), 18 (11.84%), 6 (3.94%) and 5 (3.28%) isolates for penicillin, streptomycin, erythromycin, tetracycline, ampicillin and Cephalothin, respectively. No resistance was detected for Gentamicin. Conclusion: Results indicated that these isolates exhibited the highest degree of resistance to penicillin of all antimicrobial agents tested.

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The aim of the present study was to investigate the antimicrobial and preliminary phytochemical properties of Lantana indica Roxb. The aqueous and organic solvent (ethyl acetate and methanol) extracts from the leaves of Lantana indica (Verbenaceae) were tested against Staphylococcus aureus, Bacillus subtilis, Steptococcus pyrogens, Escherichia coli, Proteus vulgaris, Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella typhi, Aspergillus niger and Candida albicans by agar well diffusion method. The results showed promising antibacterial activity against the tested bacteria. Among these, methanol and aqueous extracts were found to possess a more potent inhibitory effect when compared to the ethyl acetate extract. Preliminary phytochemical analysis of extracts revealed the presence of antimicrobial compounds such as carbohydrates, proteins, tannins and flavonoidal glycosides. The result of this study validates the use of methanol and aqueous extract of this species in ethnomedicine, favouring the isolation of antibacterial agents from the leaf extract of Lantana indica.

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