Pigmented macules of the malpighian mucous membranes have been described under numerous names since the first description by P. Laugier in 1970 of the ‘pigmentation mélanique lenticulaire essentielle de la muqueuse jugale et des lèvres’. In this paper, we show that (1) the lesions may occur in all malpighian mucous membranes, (2) are easily distinguished from melanoma both clinically and if necessary by histology, and we suggest (3) that, whichever the localization is, the condition should be called Laugier’s disease.
Summary
We report two brothers afflicted with extreme sebaceous hyperplasia of the face and the neck, with considerable sebaceous hyperplasia, but no acne. Biopsy confirmed a simple isolated sebaceous hyperplasia. This familial dermatosis has apparently not been described previously.
Summary
A 48‐year‐old Lebanese man presented with a 2‐year history of painless papules and nodules of the skin without any systematic involvement, lymphadenopathy, serum electrophoresis disturbance, leukocytosis or elevated erythrocyte sedimentation rate (ESR). The microscopic appearance was highly suggestive of sinus histiocytosis with numerous plasma cells and intense lymphophagocytosis. Rapid improvement occurred following thalidomide therapy: 300 mg a day for a month.
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