Introduction: Spatially resolved metabolic data obtained from Proton Magnetic Resonance Spectroscopy ( 1 H MRS) provides information which increases the diagnostic accuracy of imaging sequences in predicting the histology of suprasellar tumors. Aim:To evaluate the role of 1 H MRS in the diagnosis of various suprasellar tumors.
MATERIAL AND METHODS A prospective study of 100 patients in all age groups with skin lesions based on clinical data who presented to Bowring and Lady Curzon Hospital, Victoria Hospital and Vani Vilas hospital attached to Bangalore Medical College and Research Institute, Bengaluru, from November 2014 to May 2015 were subjected to HRUS examination. Study design: It was a Cross sectional study. Totally 100 patients were studied from November 2014 to May 2016. Inclusion criteria: All clinically suspected patients with superficial skin lesions. Exclusion Criteria: Patients with trauma. After taking Informed consent, all patients included A B S T R A C T Introduction: In the evaluation of cutaneous lesions, High Resolution Ultrasonography (HRUS) with color Doppler is useful as a safe, noninvasive, economical, and repeatable diagnostic procedure that can reduce and replace invasive procedures like fine needle aspirations and biopsies. Analysis of the skin surface allows the investigation of tumor and inflammatory diseases, the measurement of skin thickness. The objective of this study was to evaluate the role of HRUS in cutaneous lesions with histopathological correlation wherever possible. Material and Methods: A prospective study of 100 patients with skin lesions based on clinical data were subjected to HRUS examination. Collected data was analysed by descriptive statistics. Results: The study comprised of a total of 100 patients, out of which 75 were non-neoplastic and 25 were neoplastic lesions. The non-neoplastic lesions included Psoriasis, edema, lymph nodes and vascular malformations. The neoplastic lesions included 16 benign and 9 malignant cases. The observed HRUS and Doppler characteristics of these lesions are discussed in detail. Conclusion: HRUS is non-invasive, affordable, easily available, rapid imaging technology. It can be used to localize the skin lesion, generate differential diagnosis and to follow up known lesion.
Introduction: Computed Tomography (CT) is the first-line modality for radiologic evaluation of the orbit in the acute setting. Aim of our study was to determine the role of multi detector CT in orbital pathologies, to find the characteristics of CT in orbital pathologies and to correlate the CT findings with histopathological findings wherever possible Material and methods: The study was conducted in Department of Radiology and Imaging Sciences, Chettinad Hospital and Research Institute, Chennai. Patients with complaints related to traumatic and various non traumatic pathologies were included in our study. All CT examinations were performed using helical CT and reconstructed in appropriate planes Results: Among 102 patients included in our study, trauma constituted the most common etiology, followed by inflammatory and neoplastic. Lesions were analyzed for calcification, bony and paranasal sinus involvement, enhancement characteristics, lacrimal gland and optic nerve involvement. Conclusion: CT gives excellent details about bony anatomy in fractures and helps assessing presence or absence of foreign bodies. CT describes the extent of lesions in inflammatory and neoplastic etiologies, accurately assess bony destruction in neoplasms helping in the management of the orbital lesions
Introduction: Susceptibility Weighted Imaging (SWI) is a Magnetic Resonance Imaging (MRI) sequence aiming to enhance contrast in MR imaging. SWI is considered to be sensitive in detecting even minute amount of haemorrhage, putting in consideration that early detection of haemorrhage inside acute infarction restricts the use of thrombolytic drugs and minimise the development of large haematoma that need to be evacuated surgically thus, improving the prognosis of the patient. Aim: To evaluate and compare the diagnostic sensitivity of MR SWI with Non Enhanced Computed Tomography (NECT) and Magnetic Resonance Gradient Recalled Echo (MR GRE) sequence in detecting the early Haemorrhagic Transformation (HT) of cerebral infarction. Materials and Methods: This was a cohort study conducted from July 2018 to October 2019 on 45 patients referred to the Radiology Department of the institute with imaging findings suggestive of stroke. Apart from the NECT brain conducted on 128 slice machine and routine stroke protocol, MR SWI was also performed. MRI study was performed on 1.5 Tesla MRI scanner with a eight channel Navigator radiofrequency coil. A follow-up CT was done after 48 hours. The images obtained were subjected to radiological analysis and interpretation. Statistical Package for Social Sciences (SPSS) version 22, descriptive analysis was carried out by calculating mean±standard deviation, frequency and proportion. The collected data was compared with each other, using Chi-square test and Fisher's-exact test, correlated using Spearman Correlation test. Results: Total 45 patients (mean age: 56 years, 31 males and 14 females) were included in the study. The diagnostic sensitivity of MR SWI in detecting early HT was high 97.5% compared to 45.0% of NECT and 82.5% of MR GRE. However, the specificity of MR SWI (33.3%) and that of MR GRE (33.33%) were very low as compared to NECT (66.67%), which had a higher specificity in detection of HT. There was a weak positive correlation between surface area of bleed in GRE and surface area of bleed in SWI (Spearman’s RHO correlation 0.324, p-value 0.030). Conclusion: MR SWI had high diagnostic sensitivity in detecting HT earlier than NECT and MR GRE sequence and hence, it could play a crucial role in the treatment of patients. One of the most dreaded complications of cerebral infarction-intracerebral haemorrhage could be prevented and thus, prognosis of the patient improves. Hence, MR SWI sequence should be added to routine stroke protocol, however it cannot replace NECT, since the specificity of NECT is high compared to MR SWI.
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