Background: The purpose of this study was to specify the epidemiological and clinical characteristics of pemphigus in the Department of Dermatology of the University Hospital of Dakar. Patients and Methodology: All medical records of patients seen for pemphigus in our department over a 11-year period were analyzed retrospectively. Results: We collected 105 cases of pemphigus, corresponding to a frequency of 10 cases/year and a hospital prevalence of 2.7%. Thus, pemphigus held the second rank of blistering autoimmune bullous diseases after bullous pemphigoid. The mean age of patients was 47.62 years and the age group [40-59 years] was predominantly affected (28 cases; 45 %). There were 41 femeles and 21 men (F/M ratio: 2). We did not find an endemic focus in our country. Clinical forms were dominated by pemphigus foliaceus (30 cases; 48.5 %), followed by pemphigus vulguaris (19 cases; 30.6 %) and finally by pemphigus erythematosus (13 cases; 21%). In 16 cases (25 %), the pemphigus had begun after the consumption of a traditional medicinal plant (8 cases). An associated toxidermia was found in12 cases. Pruritus was present in 43 patients (69.35%). Discussion: In Senegal, pemphigus are common diseases, but without however an endemic focuc. They occur in young women, with a predominance of superficial forms, especially pemphigus foliaceus. The presence of pruritus and associated toxidermia to traditional medicinal plants are common.

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Introduction: Studies on erythroderma in adults are rare. The aim of this study is to specify the epidemiological and etiological characteristics of acquired erythroderma in adults in Dakar. Patients and Methodology: This was a retrospective study based on the records of patients aged over 16 years admitted for erythroderma in the Department of Dermatology of Dakar University Hospital over a period of 10 years. Results and Discussion: We collected 180 cases of adult's erythroderma corresponding to a hospital prevalence of 18 cases /year. Erythroderma represented 0.2% of all medical visits and 4.22% of admissions in our department. The mean age of patients was 45 years with a sex-ratio of 1:54. Erythroderma was in the majority, secondary to a complication of preexisting dermatoses, with eczema leading the list. The main factors leading to the exacerbation resulting in erythroderma were HIV infection and the intake of an inappropriate drug, mostly traditional plants. Conclusion: Erythroderma is a particularly frequent condition in our regions, where it is mostly caused by the exacerbation of prexisting dermatoses, often due to unsuitable treatments, such as medicinal plants.