Extensions of nuclear physics to the strange sector are reviewed, covering data and models of Λ and other hypernuclei, multistrange matter, and antikaon bound states and condensation. Past achievements are highlighted, present unresolved problems discussed, and future directions outlined.

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Experimental and theoretical developments of the last decade in the study of exotic atoms and some related low-energy reactions are reviewed, in order to provide information on the in-medium hadron-nucleon t matrix over a wide range of densities up to central nuclear densities. In particular, we review pionic deeply bound atomic states and related evidence for partial restoration of chiral symmetry in dense nuclear matter. The case for relatively narrow deeply bound atomic states for antikaons and antiprotons is made, based on the physics of strong nuclear absorption. Recent experimental suggestions for signals of antikaon-nuclear deeply bound states are reviewed, and dynamical models for calculating binding energies, widths and densities of antikaon nuclear states are discussed. Specific features of low-energy in-medium interactions of kaons, antiprotons and of Sigma hyperons are discussed, and suggestions to study experimentally Cascade atoms are reviewed.Comment: 86 pages, 44 figures, slight revisions, references added, Physics Reports (in press

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