BackgroundThe predilection site of non-occlusive mesenteric ischemia is the right-sided colon. Surgical exploration followed by segmental bowel resection and primary anastomosis or ileostomy is recommended, if vascular interventions are not feasible and conservative treatment fails. We assessed the outcome of patients in this life-threatening condition.MethodsFrom a prospective database 58 patients with urgent surgery for acute right-sided colonic ischemia without feasible vascular intervention (as a surrogate for non-occlusive mesenteric ischemia) were identified. Retrospectively the patients’ characteristics, reason for ischemia, extent of resection, rate of ileostomy creation, 30 day and one year mortality, and rate of ileostomy-reversal at one year postoperative were assessed.ResultsRadiologically mesenteric arteriosclerotic disease was present in 54% of the patients. Vaso-occlusive mesenteric disease was suspected in 15% of the patients, but not confirmed intra-operatively. Ten patients underwent (extended) right-sided hemicolectomy with primary anastomosis (30-days mortality 20%, 1-year mortality 30%). Sixteen patients had (extended) right-sided hemicolectomy with creation of an ileostomy (30-days mortality 44%, 1-year mortality 86%, ostomy reversal in one patient). Twenty-five patients had (sub-) total colectomy with ileostomy creation (30-days mortality 60%, 1-year mortality 72%, ostomy reversal in two patients). Seven patients had exploration only (30-days mortality 86%, 1-year mortality 86%). Overall, the 30-days mortality-rate was 52% and the 1-year mortality-rate was 70%. Only 7% of the patients requiring an ostomy experienced ostomy-reversal.ConclusionsPatients with urgent surgery for acute right-sided colonic ischemia without feasible vascular intervention have a very high short and long-term mortality. The rate of ostomy-reversal is very low.

Hybridbildgebung und Strahlentherapie -aktuelle Entwicklungen 125 Plotkin M et al. Prospektive multizentrische Studie … Der Nuklearmediziner 2011; 34: 125-129 Schlüsselwörter • ▶ F18-FET • ▶ Positronen-EmissionsTomografi e • ▶ Hirntumoren Key words • ▶ F18-FET • ▶ Positron-EmissionTomography • ▶ brain tumors Bibliografi e DOI http://dx.

Zusammenfassung ▼Der Stellenwert der PET mit radioaktiv markierten Aminosäuren in der neuroonkologischen Diagnostik ist in vielen Studien validiert. Die Methode kann auch bei pädiatrischen Patienten zur Früherkennung von Rezidiv-/Resttumoren und vor allem zur Differenzierung eines vitalen Tumors von therapiebedingten Veränderungen eingesetzt werden. lm Rahmen einer prospektiven, multizentrischen Studie (FET PET 2010) soll die Genauigkeit der FET-PET in der Nachsorge von kindlichen Hirntumoren im Vergleich zum gegenwärtigen diagnostischen "Goldstandard" MRT vergleichen werden. Abstract ▼The value of amino acid PET in neurooncology was validated by numerous studies. This method might be useful in paediatric patients for early diagnosis of residual/recurrent tumours and especially for differentiation of the viable tumour from therapy-induced tissue changes. The aim of a multicentre prospective study (FET PET 2010) is to estimate the accuracy of FET-PET in the follow-up of paediatric brain tumours in comparison to the current diagnostic "gold standard" MRI.Heruntergeladen von: University of Florida. Urheberrechtlich geschützt. Pädiatrische Nuklearmedizin 255Plotkin M et al. Rolle der PET in … Der Nuklearmediziner 2014; 37: 254-257

Zusammenfassung Der Stellenwert der PET mit radioaktiv markierten Aminos?uren in der neuroonkologischen Diagnostik ist in vielen Studien validiert. Die Methode kann auch bei p?diatrischen Patienten zur Fr?herkennung von Rezidiv-/Resttumoren und vor allem zur Differenzierung eines vitalen Tumors von therapiebedingten Ver?nderungen eingesetzt werden. lm Rahmen einer prospektiven, multizentrischen Studie (FET PET 2010) soll die Genauigkeit der FET-PET in der Nachsorge von kindlichen Hirntumoren im Vergleich zum gegenw?rtigen diagnostischen ?Goldstandard? MRT vergleichen werden.