This study presents an efficient synthesis of 3‐[6‐(substituted‐phenyl)‐[1,2,4]triazolo[3,4‐b][1,3,4] thiadiazol‐3‐yl]‐1H‐indazole via dehydrative condensation with cyclization of 4‐amino‐5‐(1H‐indazol‐3‐yl)‐4H‐[1,2,4]triazole‐3‐thiol and fluorinated or nonfluorinated carboxylic acids in presence of phosphorous oxychloride. The multistep reaction pathway proceeds through different compounds. Present synthesis has the advantages of easily accessible starting materials, convenient synthesis, simple reaction condition, wider substrate scope, and higher yield (75% to 90% isolated).

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6a,l2a-Dehydrorotenoids are cleanly reduced in 1,4-fashion by DIBAL to give rotenoids having the unstable, unnatural, trans-B/c fusion, readily epimerised by acid to the cis-forms: an X-ray structure for ( )-trans-isorotenone confirms the nature of the ring fusion.

Die Pictet‐Gams‐Cyclisierung der Acylaminoalkohole (I) verläuft über die Oxazoline (II), die unter schärferen Bedingungen Gemische der 3‐ bzw. 4‐substituierten l‐Phenylisochinoline (III) und (IV) geben.