The nucleotide sequence of a HindIII‐EcoRI DNA fragment, 8 kbp long, of a lambda recombinant containing the whole human c‐myc gene has been deduced by the method of Maxam and Gilbert. This fragment encodes the complex c‐myc locus and the sequence provides information relative to the 2.7 kb long c‐myc transcript. It appears that although exons 2 and 3 would code for a 48‐K protein homologous to the myc domain of the viral p110 gag‐myc protein, the first exon, which has a large open reading frame ending with a stop codon just upstream from the donor splice site, could code on its own for a 20‐K protein. Speculations about the role of that putative protein on the regulation of the expression of exons 2 and 3 are made.
The nucleotide sequence was determined of a 8775-base-pair region of DNA cloned from the photosynthetic non-sulphur bacterium Rhodospirillum rubrum. It contains a cluster of five genes encoding F1-ATPase subunits. The genes are arranged in the same order as F1 genes in the Escherichia coli unc operon. However, as in the related organism Rhodopseudomonas blastica, neither genes for components of F0, the membrane sector of ATP synthase, nor a homologue of the E. coli uncI gene are associated with this locus, as they are in E. coli.
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