Tin-free Giese reaction and the related radical carbonylation process proceeded efficiently in the presence of sodium cyanoborohydride and tetrabutylammonium cyanoborohydride. The reaction took place chemoselectively at the carbon-iodine bond but not at the carbon-bromine and carbon-chlorine bonds. The iodine atom transfer followed by hydride reduction of the resulting carbon-iodine bond is proposed as a possible mechanism.

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Die asymm. Reduktion verschiedener Substrate [(VI), (VIII), (XI), (XIII)] mit (V) ergibt mit z.T. hoher Enantioselektivität die im Formelschema aufgeführten Produkte.