Background Perioperative malnutrition is common in patients undergoing gastrointestinal-oncology surgery and is associated with longer hospital stays, increased postoperative complications, poorer quality of life, and lower survival rates. Current practice emphasizes the role of early perioperative nutrition therapy as an early intervention to combat the postoperative complications of patients and the implementation is now widely adopted. However, there is still a lack of research on determining the effectiveness of intensive nutrition therapy and providing ONS perioperative locally. This becomes the significance of this study and serves as a basis for management and guideline in the local hospital settings. Methods This is a pragmatic randomized control trial study where elective admitted patients will be randomly divided into the intervention (SS) or control (NN) group. All data will be collected during a face-to-face interview, anthropometric measurement, blood sampling (albumin, white blood count, hemoglobin, and c-reactive protein), handgrip strength, and postoperative complications. Group SS will be receiving a tailored lifestyle and intensively supplemented with oral nutrition support as compared to Group NN that will receive standard medical care. The primary outcome for this study is the length of stay in the hospital. Additional outcome measures are changes in biochemical profile and nutritional and functional status. The effects of intervention between groups on the outcome parameters will be analyzed by using the SPSS General Linear Model (GLM) for the repeated measure procedure. Discussion The intervention implemented in this study will serve as baseline data in providing appropriate nutritional management in patients undergoing gastrointestinal and oncological surgery. Trial registration ClinicalTrials.gov Protocol Registration and Results System (PRS) NCT04347772. Registered on 20 November 2019.

Background: Weight loss is well-known among head and neck (HNC) patients during radiotherapy and could continue after the treatment is completed. Weight monitoring is essential for treatment outcomes and cancer surveillance. The purpose of the study is to evaluate the weight loss during and post-treatment among HNC patients. Methods: A total of 45 out of 50 patients post-treatment were included in this secondary treatment. Data were collected at baseline, at the completion of radiotherapy and one month after completion of radiotherapy. Results: The mean weight loss was 4.53 ± 2.87 kg (7.4%) during treatment and 1.38 ± 2.65 kg (2.1%) post-treatment. There were significant improvements one month after completion of radiotherapy in Patient-Generated Subjective Global Assessment (PGSGA), muscle mass, nutrition impact symptoms (NIS) score, energy and protein from oral intake (p < 0.0001). Energy and protein from oral nutritional supplements (ONS) decreased significantly (p < 0.0001). Conclusions: The results of this study underline the importance of early identification and monitoring post-treatment in HNC patients. The post-treatment recovery stage is very important for HNC patients to ensure a healing process.

Background: Perioperative malnutrition is common in patients undergoing gastrointestinal-oncology surgical and associated with longer hospital stays, increased post-operative complications, poorer quality of life and lower survival rate. Current practice emphasises the roles of early perioperative nutrition therapy as early intervention in order to combat the post-operative complications of patients and the implementation is now widely adopted. The aim of the study is to determine the effects of intensive perioperative nutrition therapy to overcome the post-operative complications in adult patients undergoing gastrointestinal and oncological surgery. Methods: This is a pragmatic randomised control trial study where elective admitted patients will be randomised into Intervention (SS) or Control (NN) Group. All data will be collected during a face to face interview, anthropometric measurement, blood sampling (albumin, white blood count, haemoglobin and c-reactive protein), handgrip strength and post-operative complications. Group SS will be receiving a tailored lifestyle and intensively supplemented with oral nutrition support as compared with Group NN that receive standard medical care. The primary outcomes are length of stay in hospital, bowel function and solid food toleration. Additional outcome measures are changes in biochemical profile, nutritional and functional status. The effects of intervention between groups towards outcome parameters will be analyse by using the SPSS General Linear Model (GLM) for repeated measure procedure.Discussion: The intervention implemented in this study will serve as a baseline data in providing an appropriate nutritional management in patients undergoing gastrointestinal and oncological surgery. Trial registration: ClinicalTrials.gov Protocol Registration and Results System (PRS), NCT04347772. Registered 20 November 2019, https://www.clinicaltrials.gov