Background: The modified pectoral nerves block (Pecs II) as a method of analgesia for breast cancer surgery has shown excellent results in recent publications. This technique blocks the long thoracic nerve, thoracic intercostal nerves from T2-T6 & thoracodorsal nerve. Aims: To evaluate the effectiveness of the Pecs II block for pain relief in the postoperative period of patients undergoing modified radical mastectomy (MRM). Methods: A prospective comparative study was conducted at our instituition between November 2014 and March 2015. Patients scheduled to undergo MRM were randomly assigned to the test group (endotracheal anaesthesia along with Pecs II) and the control group (endotracheal anaesthesia only). In the postoperative period the patients were evaluated using a visual analogue scale to determine pain scores at 6, 12 & 24 hours. Results: Fifty patients (25 in each group), between the ages of 24 to 76 years (54.76 ± 10) were included in the study. There was no significant difference in ages between test & control groups. In the postoperative period, the test group had significantly lower median pain scores at 6, 12 & 24 hours as compared to the control group. Table 1: Comparative analysis for Pecs II block TestControlp valueeffect size (r)Average age (years)54.44 ± 10.7855.08 ± 9.370.824-Median postoperative pain scores  6 hours2 (1)6 (2)<0.001*- 0.8312 hours3 (1)5 (2)<0.001*- 0.6224 hours3 (1)0.034*- 0.30* statistically significant Conclusion: The modified pectoral nerves block (Pecs II) is a novel & effective technique for postoperative analgesia in patients undergoing modified radical mastectomy. Citation Format: Kanitkar R, Mane A, Agashe A, Kulkarni M, Deshmukh S. Modified pectoral nerves block for postoperative analgesia after modified radical mastectomy: A comparative study. [abstract]. In: Proceedings of the Thirty-Eighth Annual CTRC-AACR San Antonio Breast Cancer Symposium: 2015 Dec 8-12; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2016;76(4 Suppl):Abstract nr P2-12-13.

The modified pectoral nerves (Pecs II) block as a method of analgesia after breast cancer surgery has proven highly efficacious. This technique blocks the pectoral nerves, long thoracic nerve, thoracic intercostal nerves from T2-T6, and thoracodorsal nerve and can be effectively used as a postoperative analgesic after breast cancer surgeries. The aim of the study is to evaluate the effectiveness of the Pecs II block given intraoperatively for pain relief in the postoperative period of patients undergoing modified radical mastectomy. The outcome after intraoperative Pecs II block administration was analyzed and compared in test (general anesthesia with endotracheal intubation with Pecs II block) and control (general anesthesia with endotracheal intubation only) groups of patients (50 each) scheduled to undergo modified radical mastectomy. In the postoperative period, the patients were evaluated using a visual analogue scale to determine pain scores at 6, 12, and 24 h, and their analgesic requirements were documented. Hundred patients (50 in each group), between the ages of 24 to 76 years (54.76 ± 10), were included in the study. There was no significant difference in ages or comorbidities for test and control groups. In the postoperative period, the test group had significantly lower median pain scores at 6 and 12 h as compared with control group. The modified pectoral nerves (Pecs II) block given intraoperatively is an effective technique for postoperative analgesia in patients undergoing modified radical mastectomy.

Introduction: Induction of anaesthesia has been dominated by intravenous induction agents. The commonest induction agent in use is Sodium Thiopentone. However it is increasingly being replaced by Propofol. The advantage of propofol is faster induction, rapid and clear headed recovery and less postoperative nausea and vomiting. Very little research has been done to compare propofol with thiopentone in children. The aim of this study was to compare the anesthetic effects of thiopentone and propofol in children.

A pilot project to assess the feasibility of using epidural analgesia for labour was undertaken in an Armed Forces hospital. Effectiveness of the technique, acceptability by patients and nursing statTwas 8SS8SIIed. Forty parturients were offered labour analgesia after explaining the procedure. A single-use 16 G Romson epidural catheter was placed in 12-3 or L3-4 space. Injection bupivacaine (0.25%) 10-14 mL was used as an initial dose. An hourly dose of 0.125% bupivacaine (18-12 mL) was given till the onset ofsecond stage. Good to excellent analgesia during first stage was experienced by 34 patients. Marginal second stage prolongation was noticed but without any adverse neonatal effects. Analgesia was unsatisfactory during second stage in 25% patients. Instrumental delivery was required in 17% patients (LSCS -10% and vacuum extraction -7%). Procedure was accepted very well by 37 patients and they were satisfied with the pain relief.