Rice (Oryza sativa) plays a significant role in achieving global food security. However, it suffers from several biotic and abiotic stresses that seriously affect its production. Rice blast caused by hemibiotropic fungal pathogen Magnaporthe oryzae is one of the most widespread and devastating diseases of rice. The crop rice is vulnerable to this pathogen from seedlings to adult plant stages affecting leaves, nodes, collar, panicles and roots. This disease can be effectively managed through host resistance. Of the 100 blast resistance genes, identified and mapped in different genotypes of rice, 19 genes have been cloned and characterized at the molecular level. Most of these genes belong to nucleotide binding sites and leucine rich repeats. Besides more than 350 quantitative trait loci (QTLs) have also been identified in the rice genome. These blast resistance genes and QTLs have been successfully mobilized in the commercial cultivars by using standard plant breeding techniques and also by marker assisted backcross breeding. With the advent of latest molecular biology techniques and our understanding of the basic mechanisms of Magnaporthe-rice pathosystem, the strategies for broadspectrum resistance to M. oryzae can be designed in future.

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