Poster discussion hub abstracts other than ultrasound, follow-up beyond the age of 5 years are not different between boys and girls.
P28.05The prenatal diagnosis and outcomes of fetal lung cystic lesions: 100 cases at a single centre R. Sugibayashi, K. Ozawa, S. Wada, H. SagoCentre of Maternal-Fetal, Neonatal and Reproductive Medicine, National Centre for Child Health and Development, Tokyo, Setagaya-Ku, Japan Objectives: To investigate the relationship between the prenatal diagnosis and outcomes of fetal lung cystic lesions. Methods: We retrospectively reviewed the medical records of all patients prenatally diagnosed with congenital lung cystic lesions between 2002 and 2016 at our centre. Prenatal diagnoses were made by ultrasound. Fetal lung cystic lesions were diagnosed as bronchopulmonary sequestration (BPS) when the aberrant artery derived from the systemic circulation and as congenital pulmonary airway malformation (CPAM) when the blood supply was from normal pulmonary circulation. Macrocystic CPAMs were those with a maximum diameter of the cyst of ≥5 mm and microcystic CPAMs were those with a maximum diameter of the cyst of <5 mm. Postnatal diagnoses were made by a pathological examination after lung resection during operations, contrast-enhanced chest computed tomography or bronchoscopy. Results: Of 100 cases with prenatal diagnoses, 49 were macrocystic CPAMs, 27 were microcystic CPAMs and 24 had BPS. All prenatally diagnosed BPS cases were confirmed as BPS postnatally. The 49 prenatally diagnosed macrocystic CPAMs included 27 with CPAMs, 15 with bronchial atresia (BA), 4 with BPS and 3 others. The 27 prenatally diagnosed microcystic CPAMs included 19 with BA, 4 with CPAMs, 1 with BPS and 3 others. The maximum CPAM volume ratio at the prenatal diagnosis was significantly higher in CPAMs than in cases of BA or BPS (mean±standard deviation: 2.58±1.55 vs 1.49±1.00, 1.13±0.68). Fetal treatments was performed more often for CPAMs than in BA or BPS cases (65% vs. 18%, 17%). Postnatal surgery was performed more often and at an earlier age for CPAMs than in BA or BPS cases (94% vs. 76%, 66%, median (interquartile range): day0 (0,186) vs day366 (287,436), day293 (45,440)).
Conclusions:The prenatal diagnosis of BPS was correct. Only 55% of macrocystic CPAMs were diagnosed as CPAMs after birth, and 70% of microcystic CPAMs were diagnosed as BA postnatally. CPAMs needed surgery after birth. A more precise prenatal diagnosis of fetal lung cystic lesions is required.
P28.06Perinatal management in cases of fetal abdominal wall defects (fAWD): retrospective survey on predictors of final outcome
